Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633219 | 0.85 | TAAR1 (0.36) | TAAR1 | |
| SCHEMBL632665 | 0.84 | HTR7 (0.35) | TAAR1 | |
| SCHEMBL632226 | 0.77 | HTR2C (0.40) | TAAR1 | |
| SCHEMBL8221282 | 0.76 | TAAR1 (0.67) | TAAR1 | |
| SCHEMBL632623 | 0.76 | TAAR1 (0.38) | TAAR1 | |
| SCHEMBL632083 | 0.74 | TAAR1 (0.37) | TAAR1 | |
| SCHEMBL632031 | 0.73 | ALDH1A1 (0.40) | TAAR1 | |
| SCHEMBL631952 | 0.72 | IDO1 (0.40) | TAAR1 | |
| SCHEMBL631812 | 0.72 | TAAR1 (0.46) | TAAR1 | |
| SCHEMBL631757 | 0.71 | TAAR1 (0.39) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1081492-B1 | PACKING MATERIAL FOR CHROMATOGRAPHY HAVING NOVEL CHARACTERISTIC AND METHOD FOR ISOLATION OF SUBSTANCE USING THE SAME | CELLSEED INC (JP) | 2009-01-14 | — | — | EP | claimed |
| US-6706187-B1 | CHARGED ACRYLAMIDE POLYMER TO CHANGE THE EFFECTIVE CHARGE DENSITY OR HYDROPHILIC/HYDROPHOBIC BALANCE ON SURFACE OF A STATIONARY PHASE BY AN EXTERNAL STIMULUS, SUCH AS TEMPERATURE, WHILE FIXING A MOBILE PHASE TO AN AQUEOUS SYSTEM | Okano, Teruo (JP) | 2004-03-16 | — | — | US | claimed |
| EP-1081492-A1 | PACKING MATERIAL FOR CHROMATOGRAPHY HAVING NOVEL CHARACTERISTIC AND METHOD FOR ISOLATION OF SUBSTANCE USING THE SAME | Amersham Pharmacia Biotech K.K. (JP) | 2001-03-07 | — | — | EP | claimed |
| US-8586617-B2 | Aminomethyl-4-imidazoles | HOFFMANN-LA ROCHE INC. (US) | 2013-11-19 | — | — | US | disclosed |
| EP-2076497-B1 | AMINOMETHYL-4-IMIDAZOLES | HOFFMANN LA ROCHE (CH) | 2012-02-22 | — | — | EP | disclosed |
| EP-2076497-A1 | AMINOMETHYL-4-IMIDAZOLES | F. Hoffmann-Roche AG (CH) | 2009-07-08 | — | — | EP | disclosed |
| US-20080119535-A1 | AMINOMETHYL-4-IMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-05-22 | — | — | US | disclosed |
| WO-2008046757-A1 | AMINOMETHYL-4-IMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-04-24 | — | — | WO | disclosed |
| US-6706187-B1 | CHARGED ACRYLAMIDE POLYMER TO CHANGE THE EFFECTIVE CHARGE DENSITY OR HYDROPHILIC/HYDROPHOBIC BALANCE ON SURFACE OF A STATIONARY PHASE BY AN EXTERNAL STIMULUS, SUCH AS TEMPERATURE, WHILE FIXING A MOBILE PHASE TO AN AQUEOUS SYSTEM | Okano, Teruo (JP) | 2004-03-16 | — | — | US | disclosed |
| EP-1081492-A1 | PACKING MATERIAL FOR CHROMATOGRAPHY HAVING NOVEL CHARACTERISTIC AND METHOD FOR ISOLATION OF SUBSTANCE USING THE SAME | Amersham Pharmacia Biotech K.K. (JP) | 2001-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119535-A1 | AMINOMETHYL-4-IMIDAZOLES | INMT, HTR4, MC4R | TAAR1 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.