Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626193 | 0.99 | NPC1 (0.42) | SMN1; SMN2NPC1RAB9ALMNACES2 | |
| SCHEMBL6334265 | 0.84 | NPC1 (0.44) | SMN1; SMN2NPC1RAB9ALMNACHRM1 | |
| SCHEMBL10680751 | 0.81 | CES2 (0.47) | SMN1; SMN2LMNACES2CES1CHRM1 | |
| SCHEMBL2417875 | 0.79 | TSHR (0.53) | SMN1; SMN2NPC1RAB9ALMNACES2 | |
| SCHEMBL2419442 | 0.76 | LMNA (0.53) | SMN1; SMN2NPC1RAB9ALMNACES2 | |
| SCHEMBL2418494 | 0.74 | TSHR (0.51) | SMN1; SMN2LMNACES2CES1CHRM1 | |
| SCHEMBL19086397 | 0.74 | CES2 (0.53) | SMN1; SMN2LMNACES2CES1CHRM1 | |
| SCHEMBL28485593 | 0.73 | CES2 (0.42) | SMN1; SMN2NPC1RAB9ALMNACES2 | |
| SCHEMBL13523009 | 0.72 | MTNR1A (0.55) | CES2CES1ALDH1A1L3MBTL1 | |
| SCHEMBL280401 | 0.72 | MMP8 (0.56) | SMN1; SMN2NPC1CES2CES1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111876757-B | Preparation method of inorganic two-dimensional nano material based on plane patterning polymer brush | 华南理工大学 | 2021-09-21 | — | — | CN | claimed |
| CN-111876757-A | Preparation method of inorganic two-dimensional nano material based on plane patterning polymer brush | 华南理工大学 | 2020-11-03 | — | — | CN | claimed |
| CN-111876757-B | Preparation method of inorganic two-dimensional nano material based on plane patterning polymer brush | 华南理工大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-111876757-A | Preparation method of inorganic two-dimensional nano material based on plane patterning polymer brush | 华南理工大学 | 2020-11-03 | — | — | CN | disclosed |