Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
| ▸ | BCHE | P06276 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6334669 | 1.00 | SIGMAR1 (0.43) | SIGMAR1ACHEBCHEMEN1KMT2A | |
| SCHEMBL6334664 | 1.00 | SIGMAR1 (0.43) | SIGMAR1ACHEBCHEMEN1KMT2A | |
| SCHEMBL6339674 | 1.00 | SIGMAR1 (0.43) | SIGMAR1ACHEBCHEMEN1KMT2A | |
| SCHEMBL6339678 | 1.00 | SIGMAR1 (0.43) | SIGMAR1ACHEBCHEMEN1KMT2A | |
| SCHEMBL6335107 | 0.82 | HTR1A (0.47) | SIGMAR1ACHEBCHEMEN1KMT2A | |
| SCHEMBL6333319 | 0.77 | DRD2 (0.42) | SIGMAR1ACHEBCHEBACE1DRD2 | |
| SCHEMBL6333322 | 0.77 | DRD2 (0.42) | SIGMAR1ACHEBCHEBACE1DRD2 | |
| SCHEMBL6333323 | 0.77 | DRD2 (0.42) | SIGMAR1ACHEBCHEBACE1DRD2 | |
| SCHEMBL7141126 | 0.77 | SIGMAR1 (0.48) | SIGMAR1ACHEBCHEMEN1KMT2A | |
| SCHEMBL7141118 | 0.77 | SIGMAR1 (0.48) | SIGMAR1ACHEBCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881733-B1 | Serotonergic benzofurans | ELI LILLY AND COMPANY (US) | 2005-04-19 | — | — | US | disclosed |
| EP-1204659-B1 | SEROTONERGIC BENZOFURANS | LILLY CO ELI (US) | 2003-11-26 | — | — | EP | disclosed |