⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21573189 | 1.00 | — | — | |
| SCHEMBL20959627 | 0.84 | — | — | |
| SCHEMBL27253724 | 0.81 | — | — | |
| SCHEMBL21934762 | 0.78 | GABRP (0.39) | — | |
| SCHEMBL19817584 | 0.78 | BHMT (0.38) | — | |
| SCHEMBL22509361 | 0.77 | OPRM1 (0.54) | — | |
| SCHEMBL1704558 | 0.77 | — | — | |
| SCHEMBL20661539 | 0.76 | — | — | |
| SCHEMBL8991438 | 0.74 | — | — | |
| SCHEMBL22140645 | 0.74 | METAP2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3079015-B1 | PHOTOMASK BLANK, RESIST PATTERN FORMING PROCESS, AND METHOD FOR MAKING PHOTOMASK | SHINETSU CHEMICAL CO (JP) | 2020-04-29 | — | — | EP | disclosed |
| US-6861423-B2 | Methods of treating p38 kinase-mediated disorders with pyrido[2,3-d]pyrimidin-7-one compounds | SYNTEX (U.S.A.) LLC (US) | 2005-03-01 | — | — | US | disclosed |
| US-20040192709-A1 | 7-oxo-pyridopyrimidines (II) | SYNTEX (U.S.A.) LLC | 2004-09-30 | — | — | US | disclosed |
| US-6753427-B2 | 2,6-DISUBSTITUTED 7-OXOPYRIDO(2,3-D)PYRIMIDINES; INHIBITORS OF PROTEIN KINASES; TREATING DISEASES MEDIATED BY THE PRO-INFLAMMATORY CYTOKINES, E.G., TUMOR NECROSIS FACTOR, INTER-LEUKINS, CYCLOXYGENASE; CHRONIC OBSTRUCTIVE PULMONARY DISEASE | SYNTEX (U.S.A.) LLC | 2004-06-22 | — | — | US | disclosed |
| US-20030153586-A1 | 7-oxo-pyridopyrimidines (I) | SYNTEX (U.S.A) LLC | 2003-08-14 | — | — | US | disclosed |
| US-20030144307-A1 | 7-oxo-pyridopyrimidines (II) | ARZENO HUMBERTO BARTOLOME (US) | 2003-07-31 | — | — | US | disclosed |
| EP-1315726-A1 | 7- OXO PYRIDOPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-04 | — | — | EP | disclosed |
| US-6518276-B2 | Treating a p38 mediated disorders | SYNTEX (U.S.A.) LLC | 2003-02-11 | — | — | US | disclosed |
| US-6506749-B2 | Mitogen-activated protein kinases inhibitors | SYNTEX (U.S.A.) LLC | 2003-01-14 | — | — | US | disclosed |
| US-20020137756-A1 | Mitogen-activated protein kinases inhibitors | SYNTEX (U.S.A.) LLC | 2002-09-26 | — | — | US | disclosed |
| US-20020055513-A1 | 7-oxo-pyridopyrimidines (II) | SYNTEX (U.S.A.) LLC | 2002-05-09 | — | — | US | disclosed |
| WO-2002018380-A1 | 7-OXO PYRIDOPYRIMIDINES AS INHIBITORS OF A CELLULAR PROLIFERATION | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-07 | — | — | WO | disclosed |