Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | GLI1 | P08151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682842 | 0.86 | FDPS (0.36) | EPHX1FDPSNOS2SLC6A3SLC6A2 | |
| SCHEMBL11684883 | 0.82 | FDPS (0.36) | EPHX1FDPSNOS2NOS3NOS1 | |
| Iodoacetamide SCHEMBL11685191 | 0.82 | LMNA (0.42) | EPHX1FDPSNOS2NOS3NOS1 | |
| SCHEMBL231477 | 0.81 | — | — | |
| SCHEMBL24886 | 0.81 | — | — | |
| SCHEMBL251844 | 0.81 | — | — | |
| Acetic Acid SCHEMBL30834058 | 0.80 | SLC6A3 (0.41) | FDPSSLC6A3SLC6A2SLC6A4CYP2C9 | |
| SCHEMBL10578750 | 0.79 | — | — | |
| SCHEMBL15929564 | 0.78 | TSHR (0.45) | FDPSSLC6A3SLC6A2SLC6A4CYP2C9 | |
| Iodide SCHEMBL20815441 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911477-B2 | Muscarinic receptor agonists | PFIZER INC. (US) | 2005-06-28 | — | — | US | disclosed |
| US-20030171349-A1 | Novel muscarinic receptor agonists | VILLALOBOS ANABELLA (US) | 2003-09-11 | — | — | US | disclosed |
| US-20020103194-A1 | Novel muscarinic receptor agonists | VILLALOBOS ANABELLA (US) | 2002-08-01 | — | — | US | disclosed |
| EP-0805153-B1 | Novel muscarinic receptor agonists | PFIZER (US) | 2001-11-14 | — | — | EP | disclosed |
| US-6093733-A | FOR THE TREATMENT OR PREVENTION OF DISEASES THE TREATMENT OR PREVENTION OF WHICH IS MEDIATED BY MUSCARINIC RECEPTOR AGONISM; ALZHEIMER'S DISEASE | PFIZER INC. | 2000-07-25 | — | — | US | disclosed |
| EP-0805153-A1 | Novel muscarinic receptor agonists | PFIZER INC. (US) | 1997-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171349-A1 | Novel muscarinic receptor agonists | CHRM3, CHRM4, CHRM2 | EPHX1 767/4885FDPS 3706/4885NOS2 2019/4885 |
| US-20020103194-A1 | Novel muscarinic receptor agonists | CHRM3, CHRM4, CHRM2 | EPHX1 786/4885FDPS 3851/4885NOS2 2026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.