SCHEMBL6337034

SCHEMBL6337034

CCC(CC)Sc1ccc(Oc2ccc(C(C)=O)cn2)cc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 4/20 0.46
GRM2 Q14416 1/20 0.43
CYSLTR1 Q9Y271 1/20 0.43
LMNA P02545 1/20 0.43
OPRM1 P35372 6/20 0.41
OPRD1 P41143 6/20 0.41
OPRK1 P41145 4/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
ACACB O00763 4/20 0.40
GRN P28799 1/20 0.40
SORT1 Q99523 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6339003 0.90 MAPT (0.52) HRH3GRM2CYSLTR1LMNAOPRM1
SCHEMBL6344739 0.88 LMNA (0.55) HRH3LMNAOPRM1OPRD1OPRK1
SCHEMBL6434732 0.84 HRH3 (0.41) HRH3LMNAOPRM1OPRD1OPRK1
SCHEMBL6338939 0.81 OPRM1 (0.40) OPRM1OPRD1OPRK1ACACB
SCHEMBL20844557 0.79 OPRM1 (0.51) GRM2CYSLTR1LMNAOPRM1OPRD1
SCHEMBL25172927 0.77 MAPT (0.52) HRH3LMNAOPRM1OPRD1OPRK1
SCHEMBL19778853 0.77 KDM4E (0.56) HRH3LMNAOPRM1OPRD1OPRK1
SCHEMBL29593315 0.77 KDM4E (0.56) HRH3LMNAOPRM1OPRD1OPRK1
SCHEMBL20844518 0.76 HRH3 (0.50) HRH3LMNAOPRM1OPRD1MAPT
SCHEMBL20844579 0.76 MAOB (0.51) HRH3GRM2CYSLTR1LMNAOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 HRH3 2245/4885GRM2 3341/4885CYSLTR1 940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.