SCHEMBL6434732

SCHEMBL6434732

CCC(CC)Sc1ccc(Oc2ccc(C(=O)N(C)OC)cn2)cc1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.41
LMNA P02545 1/20 0.41
MLNR O43193 7/20 0.39
LIPE Q05469 2/20 0.38
OPRM1 P35372 6/20 0.38
OPRD1 P41143 6/20 0.38
OPRK1 P41145 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6344739 0.84 LMNA (0.55) HRH3LMNAOPRM1OPRD1OPRK1
SCHEMBL6339003 0.84 MAPT (0.52) HRH3LMNAOPRM1OPRD1OPRK1
SCHEMBL6337034 0.84 HRH3 (0.46) HRH3LMNAOPRM1OPRD1OPRK1
SCHEMBL6337027 0.76 ACACB (0.50) OPRM1OPRD1OPRK1
SCHEMBL6338939 0.75 OPRM1 (0.40) LIPEOPRM1OPRD1OPRK1
SCHEMBL1092092 0.74 MAPT (0.62)
SCHEMBL13194647 0.74 MAPT (0.47)
SCHEMBL1390119 0.73 NNMT (0.60) LMNA
SCHEMBL1092214 0.72 MAPT (0.48)
SCHEMBL21628757 0.72 ALDH1A1 (0.48) HRH3LMNAOPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 HRH3 2245/4885LMNA 4233/4885MLNR 2164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.