SCHEMBL6339003

SCHEMBL6339003

CCC(CC)Sc1ccc(Oc2ccc(C(=O)O)cn2)cc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.52
GRM2 Q14416 1/20 0.48
CYSLTR1 Q9Y271 1/20 0.48
HRH3 Q9Y5N1 2/20 0.46
HTT P42858 1/20 0.45
OPRM1 P35372 7/20 0.44
OPRD1 P41143 7/20 0.44
OPRK1 P41145 5/20 0.44
ADRB1 P08588 1/20 0.44
ADRB3 P13945 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
LMNA P02545 1/20 0.43
GRN P28799 1/20 0.42
SORT1 Q99523 1/20 0.42
HCAR3 P49019 2/20 0.42
P2RX3 P56373 1/20 0.42
HCAR2 Q8TDS4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6337034 0.90 HRH3 (0.46) MAPTGRM2CYSLTR1HRH3OPRM1
SCHEMBL6344739 0.88 LMNA (0.55) MAPTHRH3OPRM1OPRD1OPRK1
SCHEMBL6434732 0.84 HRH3 (0.41) HRH3OPRM1OPRD1OPRK1LMNA
SCHEMBL6338939 0.83 OPRM1 (0.40) OPRM1OPRD1OPRK1
SCHEMBL21656515 0.81 MAPT (0.56) MAPTGRM2CYSLTR1HRH3OPRM1
SCHEMBL21656511 0.79 MAPT (0.60) MAPTGRM2CYSLTR1OPRM1OPRD1
SCHEMBL21628634 0.77 MAPT (0.57) MAPTGRM2CYSLTR1OPRM1OPRD1
SCHEMBL6180315 0.77 MAPT (0.57) MAPTGRM2CYSLTR1HRH3OPRM1
SCHEMBL21628768 0.76 GRM2 (0.62) MAPTGRM2CYSLTR1OPRM1OPRD1
SCHEMBL4255729 0.76 RXRA (0.54) MAPTGRM2CYSLTR1HRH3OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 MAPT 2538/4885GRM2 3341/4885CYSLTR1 940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.