Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6337071 | 1.00 | CA1 (0.46) | CA1CA2CA7CA9SLC1A1 | |
| SCHEMBL2074009 | 0.85 | ALDH1A1 (0.47) | CA1CA2CA7CA9SLC1A1 | |
| SCHEMBL19944360 | 0.85 | SLC1A1 (0.46) | CA1CA2CA7CA9SLC1A1 | |
| SCHEMBL291860 | 0.81 | CA1 (0.42) | CA1CA2CA7CA9SLC1A1 | |
| SCHEMBL291859 | 0.81 | CA1 (0.42) | CA1CA2CA7CA9SLC1A1 | |
| SCHEMBL8191319 | 0.79 | CA1 (0.54) | CA1CA2CA7CA9SLC1A1 | |
| SCHEMBL8419725 | 0.79 | CA1 (0.51) | CA1CA2CA7CA9SLC1A1 | |
| SCHEMBL11447748 | 0.78 | CA1 (0.50) | CA1CA2CA7CA9SLC1A1 | |
| SCHEMBL30640944 | 0.77 | THRB (0.46) | CA1CA2CA7CA9SLC1A1 | |
| SCHEMBL30640943 | 0.77 | THRB (0.46) | CA1CA2CA7CA9SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919465-B2 | Method of preparing (3R, 3aS, 6aR)-3-hydroxyhexahydrofuro[2,3,-b] furan and related compounds | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-07-19 | — | — | US | claimed |
| US-20040127727-A1 | Method of preparing (3R, 3aS, 6aR) -3-hydroxyhexahydrofuro [2,3,-b] furan and related compounds | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, THE | 2004-07-01 | — | — | US | claimed |
| WO-2004033462-A2 | METHOD OF PREPARING (3R, 3aS, 6aR) -3- HYDROXYHEXAHYDROFURO [2, 3-b] FURAN AND RELATED COMPOUNDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2004-04-22 | — | — | WO | claimed |
| US-6919465-B2 | Method of preparing (3R, 3aS, 6aR)-3-hydroxyhexahydrofuro[2,3,-b] furan and related compounds | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-07-19 | — | — | US | disclosed |
| US-20040127727-A1 | Method of preparing (3R, 3aS, 6aR) -3-hydroxyhexahydrofuro [2,3,-b] furan and related compounds | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, THE | 2004-07-01 | — | — | US | disclosed |
| WO-2004033462-A2 | METHOD OF PREPARING (3R, 3aS, 6aR) -3- HYDROXYHEXAHYDROFURO [2, 3-b] FURAN AND RELATED COMPOUNDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2004-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127727-A1 | Method of preparing (3R, 3aS, 6aR) -3-hydroxyhexahydrofuro [2,3,-b] furan and related compounds | HSD3B1, HSD3B2, CYP1B1 | CA1 4747/4885CA2 4820/4885CA7 4242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.