Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21581925 | 0.82 | TRPM8 (0.40) | MEN1KMT2ATRPM8TRPV1HPGD | |
| SCHEMBL21611748 | 0.81 | OPRM1 (0.41) | MEN1KMT2ATRPM8TRPV1HPGD | |
| SCHEMBL29112368 | 0.74 | KMT2A (0.40) | MEN1KMT2ATRPM8TRPV1ALDH1A1 | |
| SCHEMBL29112369 | 0.74 | KMT2A (0.40) | MEN1KMT2ATRPM8TRPV1ALDH1A1 | |
| SCHEMBL24540444 | 0.74 | KMT2A (0.40) | MEN1KMT2ATRPM8TRPV1ALDH1A1 | |
| SCHEMBL24540545 | 0.74 | TRPM8 (0.52) | MEN1KMT2ATRPM8ALDH1A1SMN1; SMN2 | |
| SCHEMBL31253748 | 0.73 | EPHX1 (0.31) | TRPM8 | |
| SCHEMBL17557197 | 0.71 | ALDH1A1 (0.35) | TRPM8TRPV1ALDH1A1 | |
| SCHEMBL6337348 | 0.71 | ACACB (0.33) | MEN1KMT2ATRPV1 | |
| SCHEMBL5402271 | 0.70 | MEN1 (0.37) | MEN1KMT2ATRPM8TRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050187211-A1 | N-arylsalkyl-carboxamide compositions and methods | WEI EDWARD T (US) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187211-A1 | N-arylsalkyl-carboxamide compositions and methods | OPRL1, TRPV1, TRPA1 | MEN1 4824/4885KMT2A 3812/4885TRPM8 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.