SCHEMBL633735

SCHEMBL633735

O=C(O)C[C@H](NP)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.45
CA4 P22748 1/20 0.45
TDP1 Q9NUW8 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
SLC22A6 Q4U2R8 1/20 0.39
MME P08473 4/20 0.39
FOLH1 Q04609 1/20 0.38
RIMKLA Q8IXN7 1/20 0.38
NAALAD2 Q9Y3Q0 1/20 0.38
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
GNPAT O15228 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15071324 0.80 ALDH1A1 (0.40) TDP1SMN1; SMN2MMEFOLH1RIMKLA
SCHEMBL15731210 0.80 SLC22A6 (0.36) CA2CA4TDP1SMN1; SMN2SLC22A6
SCHEMBL27429676 0.80 CA2 (0.34) CA2CA4SMN1; SMN2MMEFOLH1
SCHEMBL22106724 0.80 ECE1 (0.44) CA2MAPT
SCHEMBL14071766 0.80 ECE1 (0.44) CA2MAPT
SCHEMBL6558713 0.79 GNPAT (0.51) CA2CA4TDP1SMN1; SMN2SLC22A6
SCHEMBL120136 0.79 CA2 (0.55) CA2CA4TDP1SMN1; SMN2MME
SCHEMBL30235634 0.79 CA2 (0.55) CA2CA4TDP1SMN1; SMN2MME
SCHEMBL14625014 0.79 GNPAT (0.51) CA2CA4TDP1SMN1; SMN2SLC22A6
SCHEMBL7080110 0.79 GNPAT (0.51) CA2CA4TDP1SMN1; SMN2SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7465716-B2 Targeted drug delivery with a hyaluronan ligand THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-12-16 US claimed
EP-1233754-A4 TARGETED DRUG DELIVERY WITH A CD44 RECEPTOR LIGAND UNIV CALIFORNIA (US) 2006-06-07 EP claimed
US-20030166602-A1 A delivery vehicle low molecular weight hyaluronan ligand, glycosaminoglycan ligand for binding to antigen, with antitumor agents, or anticancer agents SZOKA FRANCIS C (US) 2003-09-04 US claimed
US-20020131995-A1 TARGETED DRUG DELIVERY WITH A CD44 RECEPTOR LIGAND CALIFORNIA, UNIVERSITY OF THE, REGENTS OF, THE 2002-09-19 US claimed
EP-1233754-A2 TARGETED DRUG DELIVERY WITH A CD44 RECEPTOR LIGAND The Regents of The University of California (US) 2002-08-28 EP claimed
WO-2001039815-A2 TARGETED DRUG DELIVERY WITH A CD44 RECEPTOR LIGAND THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-06-07 WO claimed
CN-121574249-A Anti-CD 45 antibodies and conjugates thereof VOR生物制药股份有限公司 2026-02-27 CN disclosed
CN-121038787-A Topical PALA therapy for cancer 克利夫兰诊所基金会 2025-11-28 CN disclosed
CN-119816500-A Crystalline forms of the irreversible menin-MLL inhibitor N- [4- [4- (4-morpholinyl) -7H-pyrrolo [2,3-d ] pyrimidin-6-yl ] phenyl ] -4- [ [3 (R) - [ (1-oxo-2-propen-1-yl) amino ] -1-piperidinyl ] methyl ] -2-pyridinecarboxamide for the treatment of cancer 拜欧米富士恩公司 2025-04-11 CN disclosed
CN-115611945-B Water-soluble phosphoric acid derivative, preparation method thereof, pharmaceutical composition and application 北京森妙生物科技有限公司 2025-03-11 CN disclosed
CN-119462640-A Pyridine [3,2-d ] pyrimidine-2-amine derivative, and preparation method and application thereof 北京森妙生物科技有限公司 2025-02-18 CN disclosed
CN-114728972-B Crystalline forms of a C-C chemokine receptor type 4 antagonist and uses thereof 拉普特医疗公司 2024-12-10 CN disclosed
US-12005146-B2 Methods of treatment using cholestosome vesicles for incorporation of molecules into chylomicrons THERASYN SENSORS, INC. (US) 2024-06-11 US disclosed
US-7465716-B2 Targeted drug delivery with a hyaluronan ligand THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-12-16 US disclosed
EP-1233754-A4 TARGETED DRUG DELIVERY WITH A CD44 RECEPTOR LIGAND UNIV CALIFORNIA (US) 2006-06-07 EP disclosed
US-20030166602-A1 A delivery vehicle low molecular weight hyaluronan ligand, glycosaminoglycan ligand for binding to antigen, with antitumor agents, or anticancer agents SZOKA FRANCIS C (US) 2003-09-04 US disclosed
US-6593308-B2 Drug delivery system comprising delivery vehicle having low molecular weight hyaluronan ligand with affinity for CD44 receptors THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-07-15 US disclosed
US-20020131995-A1 TARGETED DRUG DELIVERY WITH A CD44 RECEPTOR LIGAND CALIFORNIA, UNIVERSITY OF THE, REGENTS OF, THE 2002-09-19 US disclosed
EP-1233754-A2 TARGETED DRUG DELIVERY WITH A CD44 RECEPTOR LIGAND The Regents of The University of California (US) 2002-08-28 EP disclosed
WO-2001039815-A2 TARGETED DRUG DELIVERY WITH A CD44 RECEPTOR LIGAND THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-06-07 WO disclosed