SCHEMBL14625014

SCHEMBL14625014

NN[C@H](CC(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GNPAT O15228 2/20 0.51
CA2 P00918 3/20 0.45
CA4 P22748 1/20 0.45
TDP1 Q9NUW8 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
CA1 P00915 1/20 0.40
SLC22A6 Q4U2R8 1/20 0.39
MME P08473 2/20 0.39
GABRR1 P24046 2/20 0.39
LMNA P02545 1/20 0.39
FOLH1 Q04609 1/20 0.38
RIMKLA Q8IXN7 1/20 0.38
NAALAD2 Q9Y3Q0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7080110 1.00 GNPAT (0.51) GNPATCA2CA4TDP1SMN1; SMN2
SCHEMBL6558713 1.00 GNPAT (0.51) GNPATCA2CA4TDP1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL27616755 0.97 GNPAT (0.50) GNPATCA2CA4TDP1SMN1; SMN2
SCHEMBL3469298 0.82 ECE1 (0.46) GNPATCA2CA1
SCHEMBL3821101 0.82 ECE1 (0.46) GNPATCA2CA1
Water SCHEMBL31495128 0.80 ECE1 (0.44) GNPATCA2CA1
SCHEMBL22042308 0.80 GNPAT (0.45) GNPATTDP1SMN1; SMN2LMNAFOLH1
Hydroxyamine SCHEMBL631500 0.79 CA2 (0.45) GNPATCA2CA4TDP1SMN1; SMN2
SCHEMBL633735 0.79 CA2 (0.45) GNPATCA2CA4TDP1SMN1; SMN2
SCHEMBL2916092 0.78 CA2 (0.48) CA2CA4TDP1SMN1; SMN2SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007009894-A2 PEPTIDES FOR USE IN THE TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2007-01-25 WO disclosed