SCHEMBL7080110

SCHEMBL7080110

NN[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GNPAT O15228 2/20 0.51
CA2 P00918 3/20 0.45
CA4 P22748 1/20 0.45
TDP1 Q9NUW8 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
CA1 P00915 1/20 0.40
SLC22A6 Q4U2R8 1/20 0.39
MME P08473 2/20 0.39
GABRR1 P24046 2/20 0.39
LMNA P02545 1/20 0.39
FOLH1 Q04609 1/20 0.38
RIMKLA Q8IXN7 1/20 0.38
NAALAD2 Q9Y3Q0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14625014 1.00 GNPAT (0.51) GNPATCA2CA4TDP1SMN1; SMN2
SCHEMBL6558713 1.00 GNPAT (0.51) GNPATCA2CA4TDP1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL27616755 0.97 GNPAT (0.50) GNPATCA2CA4TDP1SMN1; SMN2
SCHEMBL3469298 0.82 ECE1 (0.46) GNPATCA2CA1
SCHEMBL3821101 0.82 ECE1 (0.46) GNPATCA2CA1
Water SCHEMBL31495128 0.80 ECE1 (0.44) GNPATCA2CA1
SCHEMBL22042308 0.80 GNPAT (0.45) GNPATTDP1SMN1; SMN2LMNAFOLH1
Hydroxyamine SCHEMBL631500 0.79 CA2 (0.45) GNPATCA2CA4TDP1SMN1; SMN2
SCHEMBL633735 0.79 CA2 (0.45) GNPATCA2CA4TDP1SMN1; SMN2
SCHEMBL2916092 0.78 CA2 (0.48) CA2CA4TDP1SMN1; SMN2SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117597407-A Silicone modified polyurea coating compositions PPG工业俄亥俄公司 2024-02-23 CN claimed
CN-111165710-A Bifidobacterium bifidum probiotic solid beverage with cell aging resistance 任彦芬 2020-05-19 CN claimed
CN-103635501-A Pavement marking composition system 3M INNOVATIVE PROPERTIES CO 2014-03-12 CN claimed
EP-3355885-B1 POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE ELYSIUM THERAPEUTICS INC (US) 2026-02-25 EP disclosed
WO-2025216797-A1 DOSING OF POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE ELYSIUM THERAPEUTICS, INC. (US) 2025-10-16 WO disclosed
US-20250250340-A1 METHOD TO PURIFY AN ANTIBODY COMPOSITION Dr Reddy’s Laboratories Ltd (IN) 2025-08-07 US disclosed
US-12319940-B2 Methods for purification of arylsulfatase A TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-06-03 US disclosed
US-20250161468-A1 POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE ELYSIUM THERAPEUTICS, INC. 2025-05-22 US disclosed
CN-119979504-A Process for purifying arylsulfatase A 武田药品工业株式会社 2025-05-13 CN disclosed
EP-4545141-A2 PURIFIED ARYLSULFATASE A AND COMPOSITIONS THEREOF Takeda Pharmaceutical Company Limited (JP) 2025-04-30 EP disclosed
US-20250073320-A1 PURIFIED ARYLSULFATASE A AND COMPOSITIONS THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-03-06 US disclosed
CN-1630516-A Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents UAB RESEARCH FOUNDATION (US) 2005-06-22 CN disclosed
CN-1191288-C Crosslinking process 3M INNOVATIVE PROPERTIES CO (US) 2005-03-02 CN disclosed
CN-1128170-C Liquid pavement marking composation MINNESOTA MINING & MFG (US) 2003-11-19 CN disclosed
EP-1322616-A2 QUINOLINE-(C=O)-(DI-, TRI- AND TETRAPEPTIDE) DERIVATIVES AS CASPASE INHIBITORS ENZYME SYSTEMS PRODUCTS INC. (US) 2003-07-02 EP disclosed
CN-1413224-A Crosslinking process 3M INNOVATIVE PROPERTIES CO (US) 2003-04-23 CN disclosed
WO-2002018341-A9 QUINOLINE- (C=O) - (DI-, TRI- AND TETRAPEPTIDE) DERIVATIVES AS CASPASE INHIBITORS ENZYME SYST PROD INC (US) 2002-11-21 WO disclosed
US-20020052323-A1 Quinoline-(C=O)-(multiple amino acids)-leaving group compounds for pharmaceutical compositions and reagents MP BIOMEDICALS, LLC 2002-05-02 US disclosed
WO-2002018341-A2 QUINOLINE- (C=O) - (DI-, TRI- AND TETRAPEPTIDE) DERIVATIVES AS CASPASE INHIBITORS ENZYME SYSTEMS PRODUCTS, INC. (US) 2002-03-07 WO disclosed
CN-1260808-A Liquid pavement marking composation MINNESOTA MINING & MFG (US) 2000-07-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161468-A1 POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE OPRM1, OPRK1, OPRL1 GNPAT 476/4885CA2 2468/4885CA4 2919/4885
US-20020052323-A1 Quinoline-(C=O)-(multiple amino acids)-leaving group compounds for pharmaceutical compositions and reagents CASP3, CASP1, BAX GNPAT 4394/4885CA2 3187/4885CA4 2876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.