SCHEMBL6337447

SCHEMBL6337447

CCOC(=O)c1ccc(Oc2ccc3cc(OCc4ccccc4)ccc3c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
HSP90AA1 P07900 1/20 0.60
MAOB P27338 5/20 0.57
ALOX5 P09917 1/20 0.52
PPARG P37231 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.51
MRGPRX4 Q96LA9 1/20 0.51
MAPT P10636 4/20 0.51
NPSR1 Q6W5P4 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
NPC1 O15118 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
LMNA P02545 1/20 0.50
GABRA1 P14867 1/20 0.50
GABRG2 P18507 1/20 0.50
GABRB3 P28472 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19490437 0.93 L3MBTL1 (0.56) MEN1KMT2AHSP90AA1MAOBPPARG
SCHEMBL340618 0.87 MAOB (0.67) KMT2AMAOBPPARGSMN1; SMN2MAPT
SCHEMBL6751328 0.86 MEN1 (0.55) MEN1KMT2AHSP90AA1MAOBALOX5
SCHEMBL6338480 0.84 MAOB (0.73) MAOBALOX5SMN1; SMN2MRGPRX4MAPT
SCHEMBL6342568 0.84 NR4A2 (0.71) MEN1KMT2AMAOBALOX5SMN1; SMN2
SCHEMBL977234 0.83 SRD5A2 (0.68) MAOBPPARGSMN1; SMN2MAPTL3MBTL1
SCHEMBL3235219 0.81 ALOX5 (0.61) MEN1KMT2AMAOBALOX5SMN1; SMN2
SCHEMBL11602002 0.81 SMN1; SMN2 (0.61) MEN1KMT2AMAOBSMN1; SMN2MAPT
SCHEMBL5836718 0.81 SLC6A2 (0.67) MEN1KMT2AMAOBSMN1; SMN2MAPT
SCHEMBL7841771 0.81 MAOB (0.58) MEN1KMT2AHSP90AA1MAOBALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 MEN1 2656/4885KMT2A 1762/4885HSP90AA1 491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.