SCHEMBL6337667

SCHEMBL6337667

CC(=O)c1ccc(Oc2ccc(OCc3ccccc3)cc2)cc1

nearest known ligand 0.90

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 13/20 0.90
ALDH1A1 P00352 1/20 0.75
HTT P42858 1/20 0.75
SMN1; SMN2 Q16637 1/20 0.75
L3MBTL1 Q9Y468 1/20 0.75
NR4A1 P22736 1/20 0.68
NR4A2 P43354 1/20 0.68
NR4A3 Q92570 1/20 0.68
MAOA P21397 2/20 0.65
PARP10 Q53GL7 1/20 0.64
SRD5A2 P31213 1/20 0.62
MAPT P10636 1/20 0.61
HPGD P15428 1/20 0.61
RAB9A P51151 1/20 0.61
PLA2G4B P0C869 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11845043 0.95 MAOB (0.82) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL42302 0.95 MAOB (1.00) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL9126144 0.90 MAOB (0.90) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL6338480 0.90 MAOB (0.73) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL13513249 0.88 MAOB (0.87) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL27518404 0.88 MAOB (0.85) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL1221359 0.87 NR4A2 (0.90) MAOBSMN1; SMN2NR4A1NR4A2NR4A3
SCHEMBL17602370 0.86 MAOB (0.82) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL29154487 0.86 ALDH1A1 (0.83) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL6054433 0.86 MAOB (0.82) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 MAOB 2681/4885ALDH1A1 250/4885HTT 4278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.