SCHEMBL633865

SCHEMBL633865

CCC=CCCOc1ccccc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
KMT2A Q03164 3/20 0.59
PTK2B Q14289 1/20 0.59
KDM4E B2RXH2 8/20 0.52
HTT P42858 3/20 0.50
NPC1 O15118 1/20 0.49
CYP2C9 P11712 1/20 0.49
RAB9A P51151 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
LMNA P02545 4/20 0.49
MAPT P10636 3/20 0.49
MEN1 O00255 2/20 0.49
NR1I2 O75469 1/20 0.49
CHRM2 P08172 1/20 0.49
CYP3A4 P08684 1/20 0.49
ADRA2A P08913 1/20 0.49
OPRK1 P41145 1/20 0.49
HTR2B P41595 1/20 0.49
SLC6A3 Q01959 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300776 1.00 ALDH1A1 (0.59) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL5056709 0.91 ALDH1A1 (0.52) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL23748684 0.87 ALDH1A1 (0.44) ALDH1A1KMT2APTK2BKDM4ENPC1
SCHEMBL28620825 0.87 ALDH1A1 (0.44) ALDH1A1KMT2APTK2BKDM4ENPC1
SCHEMBL25194130 0.87 KDM4E (0.51) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL25265029 0.87 KDM4E (0.51) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL31109156 0.82 ALDH1A1 (0.56) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL2887745 0.81 KMT2A (0.59) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL7710661 0.81 KMT2A (0.63) ALDH1A1KMT2APTK2BKDM4ENPSR1
SCHEMBL6925754 0.81 KMT2A (0.59) ALDH1A1KMT2APTK2BKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2662434-B2 Use of specific compounds for enhancing odours SYMRISE AG (DE) 2023-08-16 EP claimed
US-11179310-B2 Fragrance compositions and products with mood enhancing effects SYMRISE AG (DE) 2021-11-23 US claimed
EP-3621577-B1 NOVEL FRAGRANCE COMPOSITIONS AND PRODUCTS WITH MOOD ENHANCING EFFECTS SYMRISE AG (DE) 2021-06-30 EP claimed
CN-104837973-B Fragrance materials 宝洁公司 2020-04-21 CN claimed
EP-2662434-B1 Use of specific compounds for enhancing odours SYMRISE AG (DE) 2018-03-21 EP claimed
EP-1448757-B2 PRO-PERFUME COMPOSITIONS USED IN CLEANING OR FABRIC TREATMENT PRODUCTS PROCTER & GAMBLE (US) 2015-04-08 EP claimed
EP-1448757-B1 PRO-PERFUME COMPOSITIONS USED IN CLEANING OR FABRIC TREATMENT PRODUCTS PROCTER & GAMBLE (US) 2012-05-30 EP claimed
EP-1848702-A2 PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS Flexitral, Inc. (US) 2007-10-31 EP claimed
US-20060205632-A1 Pro-fragrance and pro-flavorant compositions FLEXITRAL, INC. 2006-09-14 US claimed
WO-2006085048-A2 PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS FLEXITRAL, INC. (US) 2006-08-17 WO claimed
US-6858575-B2 Pro-perfume compositions and substrate-treating products and methods using them PROCTER & GAMBLE COMPANY (US) 2005-02-22 US claimed
US-20030171250-A1 Pro-perfume compositions and substrate-treating products and methods using them THE PROCTER & GAMBLE COMPANY 2003-09-11 US claimed
EP-1314777-A1 Pro-perfume compositions used in cleaning or fabric treatment products THE PROCTER & GAMBLE COMPANY (US) 2003-05-28 EP claimed
EP-3684898-B1 METHOD FOR PRODUCING AN ACTIVE SUBSTANCE WAFER SYMRISE AG (DE) 2025-04-30 EP disclosed
EP-3438137-B1 MODIFIED HYDROCARBON RESIN AND HOT-MELT ADHESIVE COMPOSITION ZEON CORP (JP) 2024-01-31 EP disclosed
EP-3604356-B1 MODIFIED HYDROCARBON RESIN ZEON CORP (JP) 2023-08-02 EP disclosed
US-5837671-A ETHYL OCTADIENOATE FOR TASTE AND ODOR GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) 1998-11-17 US disclosed
EP-0761808-A2 Use of substituted lactones as perfuming agent HAARMANN & REIMER GMBH (DE) 1997-03-12 EP disclosed
EP-0094722-B1 10-ISOPROPYL-2,7-DIMETHYL-1-OXASPIRO(4.5)DECA-3,6-DIENE, ITS USE IN PERFUMES AND AROMAS NAARDEN INTERNATIONAL N.V. (NL) 1986-02-26 EP disclosed
EP-0094722-A1 10-Isopropyl-2,7-dimethyl-1-oxaspiro(4.5)deca-3,6-diene, its use in perfumes and aromas NAARDEN INTERNATIONAL N.V. (NL) 1983-11-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030171250-A1 Pro-perfume compositions and substrate-treating products and methods using them FASN, ALOX5, PAM ALDH1A1 333/4885KMT2A 2935/4885PTK2B 3705/4885
US-20060205632-A1 Pro-fragrance and pro-flavorant compositions TAS2R10, TAS2R9, OR10J3 ALDH1A1 1201/4885KMT2A 3814/4885PTK2B 4409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.