SCHEMBL633875

SCHEMBL633875

NNS(=O)(=O)Nc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.60
CA1 P00915 3/20 0.60
KEAP1 Q14145 3/20 0.54
IL1RN P18510 1/20 0.52
ERAP1 Q9NZ08 1/20 0.52
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
ALDH1A1 P00352 1/20 0.48
PKM P14618 1/20 0.48
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
IDO1 P14902 1/20 0.46
CYP2C19 P33261 1/20 0.46
PTGS2 P35354 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
POLB P06746 1/20 0.44
CA12 O43570 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL59151 0.85 KEAP1 (0.64) CA2CA1KEAP1IL1RNERAP1
SCHEMBL23141160 0.82 KEAP1 (0.61) CA2CA1KEAP1IL1RNERAP1
SCHEMBL9464302 0.77 KMT2A (0.66) CA2CA1KEAP1IL1RNERAP1
SCHEMBL28590445 0.76 CA2 (0.54) CA2CA1KEAP1IL1RNERAP1
SCHEMBL841252 0.76 KEAP1 (0.60) CA2CA1KEAP1IL1RNERAP1
Phenylsulfamide SCHEMBL27994318 0.75 CA1 (1.00) CA2CA1KEAP1IL1RNERAP1
Phenylsulfamide SCHEMBL253104 0.75 CA1 (1.00) CA2CA1KEAP1IL1RNERAP1
Water SCHEMBL27995894 0.74 CA2 (0.52) CA2CA1KEAP1IL1RNERAP1
SCHEMBL10531562 0.74 CA2 (0.52) CA2CA1KEAP1IL1RNERAP1
SCHEMBL3802959 0.74 CA1 (0.52) CA2CA1KEAP1IL1RNERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2302000-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2016-11-16 EP disclosed
US-9051501-B2 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2015-06-09 US disclosed
EP-2100923-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2013-03-13 EP disclosed
EP-2088173-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2012-02-22 EP disclosed
US-8008386-B2 Curable composition KANEKA CORPORATION (JP) 2011-08-30 US disclosed
EP-2302000-A1 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2011-03-30 EP disclosed
US-20100063215-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2010-03-11 US disclosed
US-20100041810-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORPORATION (JP) 2010-02-18 US disclosed
EP-2100923-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2009-09-16 EP disclosed
EP-2088173-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION Kaneka Corporation (JP) 2009-08-12 EP disclosed