SCHEMBL841252

SCHEMBL841252

CNS(=O)(=O)Nc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.60
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
IL1RN P18510 1/20 0.52
ERAP1 Q9NZ08 1/20 0.52
CA12 O43570 3/20 0.48
CA9 Q16790 3/20 0.48
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
ALDH1A1 P00352 1/20 0.48
PKM P14618 1/20 0.48
TSHR P16473 1/20 0.46
GAA P10253 1/20 0.43
PGR P06401 2/20 0.42
SLC40A1 Q9NP59 1/20 0.42
NR3C2 P08235 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL59151 0.85 KEAP1 (0.64) KEAP1CA1CA2IL1RNERAP1
SCHEMBL23141160 0.82 KEAP1 (0.61) KEAP1CA1CA2IL1RNERAP1
SCHEMBL9092231 0.81 KEAP1 (0.60) KEAP1CA1CA2IL1RNERAP1
SCHEMBL15448405 0.79 CA1 (0.59) CA1CA2CA12CA9KMT2A
SCHEMBL5388760 0.77 ALDH1A1 (0.36) KEAP1CA1CA2IL1RNERAP1
SCHEMBL9464922 0.77 KEAP1 (0.50) KEAP1CA1CA2CA9KMT2A
SCHEMBL22638695 0.77 CA12 (0.51) CA1CA2CA12CA9KMT2A
SCHEMBL10192105 0.77 HPGD (0.53) KMT2AMEN1ALDH1A1PKMGAA
SCHEMBL28590445 0.76 CA2 (0.54) KEAP1CA1CA2IL1RNERAP1
SCHEMBL633875 0.76 CA2 (0.60) KEAP1CA1CA2IL1RNERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113087687-A Method for direct carbon-hydrogen alkynylation of thioamide-oriented aromatic hydrocarbon 宁夏大学 2021-07-09 CN claimed
JP-2597176-B2 1997-04-02 JP claimed
WO-1988005630-A1 FUNGICIDAL COMPOSITIONS SHELL AGRAR GMBH & CO. KG (DE) 1988-08-11 WO claimed
WO-2021155004-A1 STRAD-BINDING AGENTS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-08-05 WO disclosed
US-20170015649-A1 N-Thio-anthranilamid compounds and their use as pesticides BASF SE (DE) 2017-01-19 US disclosed
US-9365543-B2 N-Thio-anthranilamid compounds and their use as pesticides BASF SE 2016-06-14 US disclosed
US-20150353523-A1 N-Thio-anthranilamid compounds and their use as pesticides BASF SE (DE) 2015-12-10 US disclosed
EP-1238989-B1 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS INC (JP) 2015-10-07 EP disclosed
US-9056853-B2 N-Thio-anthranilamid compounds and their use as pesticides BASF SE (DE) 2015-06-16 US disclosed
US-20140378458-A1 N-Thio-anthranilamid compounds and their use as pesticides BASF SE (DE) 2014-12-25 US disclosed
US-8772289-B2 N-Thio-anthranilamid compounds and their use as pesticides BASF SE (DE) 2014-07-08 US disclosed
CN-100390236-C Method for preparing tetrazo pigment TOYO INK MFG CO (JP) 2008-05-28 CN disclosed
EP-1904475-A1 N-THIO-ANTHRANILAMID COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2008-04-02 EP disclosed
WO-2007006670-A1 N-THIO-ANTHRANILAMID COMPOUNDS AND THEIR USE AS PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-18 WO disclosed
US-6897176-B2 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS, INC. (JP) 2005-05-24 US disclosed
US-20020169072-A1 Olefin polymerization catalyst and process for produing Olefin polymer with the catalyst MITSUI CHEMICALS, INC. (JP) 2002-11-14 US disclosed
EP-1238989-A2 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst Mitsui Chemicals, Inc. (JP) 2002-09-11 EP disclosed
CN-1317517-A Method for preparing tetrazo pigment TOYO INK MFG CO (JP) 2001-10-17 CN disclosed
WO-1993024008-A2 MIXTURES OF ACTIVE ANTI-MICROBIAL SUBSTANCES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1993-12-09 WO disclosed
EP-0021176-B1 CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1984-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140378458-A1 N-Thio-anthranilamid compounds and their use as pesticides NAT1, AAAS, ACHE KEAP1 930/4885CA1 303/4885CA2 1085/4885
US-20170015649-A1 N-Thio-anthranilamid compounds and their use as pesticides NAT1, AAAS, ACHE KEAP1 930/4885CA1 303/4885CA2 1085/4885
US-20150353523-A1 N-Thio-anthranilamid compounds and their use as pesticides NAT1, AAAS, ACHE KEAP1 930/4885CA1 303/4885CA2 1085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.