Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ALPG | P10696 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2088415 | 0.79 | AOC3 (0.39) | SMN1; SMN2LMNAALDH1A1ALPGTDP1 | |
| SCHEMBL9493695 | 0.79 | GAA (0.45) | SMN1; SMN2LMNAALDH1A1TDP1AOC3 | |
| SCHEMBL1275688 | 0.78 | TRPA1 (0.46) | SMN1; SMN2LMNAALDH1A1TDP1AOC3 | |
| SCHEMBL3447644 | 0.78 | TRPA1 (0.46) | SMN1; SMN2LMNAALDH1A1TDP1AOC3 | |
| SCHEMBL11234788 | 0.73 | MAPT (0.39) | SMN1; SMN2LMNAALDH1A1ALPGTDP1 | |
| SCHEMBL7865916 | 0.71 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAALDH1A1ALPGTDP1 | |
| SCHEMBL8088810 | 0.71 | LMNA (0.46) | SMN1; SMN2LMNAALDH1A1ALPGTDP1 | |
| SCHEMBL5313336 | 0.71 | LMNA (0.39) | SMN1; SMN2LMNAALDH1A1ALPGTDP1 | |
| SCHEMBL9491754 | 0.71 | SLC6A3 (0.46) | SMN1; SMN2LMNAALDH1A1HTTSLC6A2 | |
| SCHEMBL16226833 | 0.70 | AOC3 (0.45) | AOC3SLC6A2SLC6A4SLC6A3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6956132-B2 | Process for producing 2-phenylacetophenone derivatives and precursors therefor | ISHIHARA SANGYO KAISHA. LTD. (JP) | 2005-10-18 | — | — | US | disclosed |
| US-20040176644-A1 | Process for producing 2-phenylacetophenone derivatives and precursons therefor | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176644-A1 | Process for producing 2-phenylacetophenone derivatives and precursons therefor | CYP2A6, CYP2B6, CYP1B1 | SMN1; SMN2 4848/4885LMNA 4289/4885ALDH1A1 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.