Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14330644 | 0.80 | GAA (0.40) | GAAADRB2ALDH1A1AOC3L3MBTL1 | |
| SCHEMBL1995041 | 0.79 | ADRB2 (0.40) | GAAADRB2AOC3TSHRMAPK1 | |
| SCHEMBL6340375 | 0.79 | SMN1; SMN2 (0.42) | ALDH1A1AOC3L3MBTL1TDP1LMNA | |
| SCHEMBL9491754 | 0.79 | SLC6A3 (0.46) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1275688 | 0.78 | TRPA1 (0.46) | GAAALDH1A1AOC3L3MBTL1TSHR | |
| SCHEMBL3447644 | 0.78 | TRPA1 (0.46) | GAAALDH1A1AOC3L3MBTL1TSHR | |
| SCHEMBL10958098 | 0.77 | AOC3 (0.43) | GAAALDH1A1AOC3TSHRTDP1 | |
| SCHEMBL11229208 | 0.75 | GAA (0.42) | GAAADRB2ALDH1A1AOC3L3MBTL1 | |
| SCHEMBL7818955 | 0.73 | CHRM2 (0.43) | GAAALDH1A1AOC3L3MBTL1BRD4 | |
| SCHEMBL11234788 | 0.73 | MAPT (0.39) | ALDH1A1L3MBTL1MAPK1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361990-B1 | DISUBSTITUTED BENZYLAMINES, THE PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND THEIR SYNTHESES INTERMEDIATES | JOUVEINAL S.A. (FR) | 1993-02-24 | — | — | EP | disclosed |
| EP-0361990-A1 | Disubstituted benzylamines, the process for their preparation, their use as drugs and their syntheses intermediates | JOUVEINAL S.A. (FR) | 1990-04-04 | — | — | EP | disclosed |