SCHEMBL6340722

SCHEMBL6340722

COC(=O)c1ccccc1N(C(C)=O)c1ccc(Oc2ccc3cc(OCc4ccccc4)ccc3c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.44
ALOX5 P09917 2/20 0.42
TSPO P30536 3/20 0.41
MEN1 O00255 1/20 0.41
HSP90AA1 P07900 1/20 0.41
KMT2A Q03164 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
ALDH1A1 P00352 1/20 0.41
NOX1 Q9Y5S8 2/20 0.40
HIF1A Q16665 1/20 0.40
MAOA P21397 1/20 0.40
ACACB O00763 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
FLT3 P36888 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6405714 0.93 ALOX5 (0.47) MAOBALOX5TSPOPTGS1PTGS2
SCHEMBL6404636 0.86 KMT2A (0.44) TSPOMEN1KMT2A
SCHEMBL8027772 0.86 TSPO (0.53) ALOX5TSPOMEN1KMT2APTGS1
SCHEMBL8041211 0.85 FFAR1 (0.44) MAOBTSPOHIF1A
SCHEMBL8037973 0.84 CNR1 (0.43) MAOBMEN1KMT2AHIF1AMAOA
SCHEMBL8027787 0.84 MRGPRX4 (0.46) MAOBTSPOKMT2AHIF1AMAOA
SCHEMBL8044225 0.84 ALOX5 (0.45) MAOBALOX5TSPOPTGS1PTGS2
SCHEMBL6408806 0.83 ALOX5 (0.50) MAOBALOX5TSPOPTGS1PTGS2
SCHEMBL8037899 0.82 MAPT (0.51) TSPOKMT2AALDH1A1
SCHEMBL6403207 0.81 TSPO (0.45) TSPOMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1245380-C Anthranilic acid derivatives TEIJIN LTD (JP) 2006-03-15 CN disclosed
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
US-20050027008-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredient TEIJIN LIMITED 2005-02-03 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-20030220402-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredients TEIJIN LIMITED (JP) 2003-11-27 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1256341-A1 CANCER REMEDY COMPRISING ANTHRANILIC ACID DERIVATIVE AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 2002-11-13 EP disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030220402-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredients HCCS, BCOR, CBR1 MAOB 1744/4885ALOX5 403/4885TSPO 769/4885
US-20050027008-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredient CA9, HCCS, CA7 MAOB 1070/4885ALOX5 324/4885TSPO 678/4885
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 MAOB 2681/4885ALOX5 620/4885TSPO 1067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.