Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TSPO | P30536 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037870 | 0.92 | LTA4H (0.46) | MAPTRAB9ATSPOLTA4HTDP1 | |
| SCHEMBL8037882 | 0.90 | LTA4H (0.48) | MAPTTSPOLTA4HTSHRCYP1A2 | |
| SCHEMBL8038284 | 0.89 | ALDH1A1 (0.49) | MAPTRAB9ATSPOLTA4HALDH1A1 | |
| SCHEMBL6405714 | 0.89 | ALOX5 (0.47) | RAB9ATSPOALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8041192 | 0.88 | TSPO (0.41) | MAPTRAB9ATSPOLTA4HTDP1 | |
| SCHEMBL8044175 | 0.86 | TSPO (0.43) | MAPTTSPOTDP1TSHRALDH1A1 | |
| SCHEMBL6403207 | 0.85 | TSPO (0.45) | TSPOLTA4HTDP1TSHRALDH1A1 | |
| SCHEMBL8039724 | 0.84 | TSPO (0.41) | MAPTRAB9ATSPOTDP1TSHR | |
| SCHEMBL8039723 | 0.82 | PNLIP (0.47) | MAPTTSPOTDP1TSHRALDH1A1 | |
| SCHEMBL8041238 | 0.82 | LTA4H (0.51) | LTA4HTSHRPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |