SCHEMBL6403207

SCHEMBL6403207

COC(=O)c1ccccc1N(C(C)=O)c1ccc(Oc2ccc(O)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 2/20 0.45
KMT2A Q03164 2/20 0.44
LMNA P02545 2/20 0.42
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 1/20 0.39
LTA4H P09960 2/20 0.39
NR1H2 P55055 1/20 0.39
BAX Q07812 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TP53 P04637 1/20 0.38
BACE1 P56817 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
CFTR P13569 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PNLIP P16233 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6404636 0.91 KMT2A (0.44) TSPOKMT2ALMNATSHRMEN1
SCHEMBL8044308 0.87 PTPN1 (0.45) TSPOKMT2ALMNATSHRLTA4H
SCHEMBL8039723 0.86 PNLIP (0.47) TSPOKMT2ALMNATSHRTDP1
SCHEMBL6405714 0.86 ALOX5 (0.47) TSPOALDH1A1SMN1; SMN2
SCHEMBL8037899 0.85 MAPT (0.51) TSPOKMT2ATSHRTDP1LTA4H
SCHEMBL8037870 0.84 LTA4H (0.46) TSPOKMT2ALMNATSHRTDP1
SCHEMBL8044175 0.83 TSPO (0.43) TSPOKMT2ATSHRTDP1ALDH1A1
SCHEMBL8037882 0.83 LTA4H (0.48) TSPOLMNATSHRLTA4HSMN1; SMN2
SCHEMBL8037891 0.83 TSPO (0.40) TSPOKMT2ALMNATSHRALDH1A1
SCHEMBL8638319 0.82 TSPO (0.41) TSPOKMT2ATDP1LTA4HNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050027008-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredient TEIJIN LIMITED 2005-02-03 US disclosed
US-20030220402-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredients TEIJIN LIMITED (JP) 2003-11-27 US disclosed
EP-1256341-A1 CANCER REMEDY COMPRISING ANTHRANILIC ACID DERIVATIVE AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 2002-11-13 EP disclosed
EP-0806412-B1 BENZENE DERIVATIVES TEIJIN LTD (JP) 2000-04-05 EP disclosed
US-5808144-A ANTIALLERGENS TEIJIN LIMITED (JP) 1998-09-15 US disclosed
EP-0806412-A1 BENZENE DERIVATIVES TEIJIN LIMITED (JP) 1997-11-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030220402-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredients HCCS, BCOR, CBR1 TSPO 769/4885KMT2A 553/4885LMNA 2685/4885
US-20050027008-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredient CA9, HCCS, CA7 TSPO 678/4885KMT2A 799/4885LMNA 3409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.