SCHEMBL63413

SCHEMBL63413

CCOc1ccc(NC=C(C(=O)O)C(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.56
RAB9A P51151 3/20 0.56
PKM P14618 1/20 0.56
KMT2A Q03164 2/20 0.54
CYP1A2 P05177 2/20 0.54
POLB P06746 1/20 0.54
MEN1 O00255 1/20 0.54
LMNA P02545 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALDH1A1 P00352 2/20 0.53
DHODH Q02127 1/20 0.53
MAPT P10636 4/20 0.50
EGFR P00533 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
HPGD P15428 1/20 0.49
NPSR1 Q6W5P4 1/20 0.47
HTT P42858 1/20 0.47
MAPK1 P28482 1/20 0.47
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL5575001 0.97 NPC1 (0.53) NPC1RAB9APKMKMT2ACYP1A2
SCHEMBL7071412 0.90 DHODH (0.65) NPC1RAB9APKMKMT2ACYP1A2
SCHEMBL8035220 0.90 DHODH (0.65) NPC1RAB9APKMKMT2ACYP1A2
SCHEMBL1986585 0.86 KMT2A (0.57) NPC1RAB9APKMKMT2ACYP1A2
SCHEMBL7071410 0.86 DHODH (0.59) NPC1RAB9APKMKMT2ACYP1A2
SCHEMBL62489 0.85 NPC1 (0.46) NPC1RAB9APKMKMT2ACYP1A2
SCHEMBL62488 0.84 DHODH (0.75) KMT2ACYP1A2POLBMEN1LMNA
SCHEMBL27661620 0.84 NPC1 (0.56) NPC1RAB9APKMKMT2ACYP1A2
Bicarbonate SCHEMBL4601785 0.84 KMT2A (0.58) NPC1RAB9APKMKMT2ACYP1A2
SCHEMBL3824701 0.81 ALDH1A1 (0.59) NPC1RAB9APKMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1727515-B1 UV ABSORBING CHROMOPHORES COVALENTLY BONDED TO HYPERBRANCHED POLYMERS DSM IP ASSETS BV (NL) 2014-04-30 EP claimed
EP-1807452-B1 ADDITIVE FOR UV-SUNSCREEN PREPARATIONS DSM IP ASSETS BV (NL) 2013-05-08 EP claimed
EP-1722863-B1 MICROCAPSULES WITH UV FILTER ACTIVITY AND PROCESS FOR PRODUCING THEM DSM IP ASSETS BV (NL) 2012-02-08 EP claimed
CN-1889920-B Microcapsules with uv filter activity and process for producing them DSM IP ASSETS BV 2011-04-13 CN claimed
CN-1889920-A Microcapsules with uv filter activity and process for producing them DSM IP ASSETS BV (NL) 2007-01-03 CN claimed
EP-3709956-B1 COSMETIC OR DERMATOLOGICAL COMPOSITIONS DSM IP ASSETS BV (NL) 2024-10-23 EP disclosed
US-11207256-B2 Method for solubilizing poorly water-soluble cosmetic agents ATHENION AG (CH) 2021-12-28 US disclosed
EP-2032115-B1 COMPOSITIONS BASED ON HYPERBRANCHED CONDENSATION POLYMERS AND NOVEL HYPERBRANCHED CONDENSATION POLYMERS DSM IP ASSETS BV (NL) 2021-07-21 EP disclosed
CN-107072902-B Use of cosmetic compositions comprising 10-hydroxystearic acid 帝斯曼知识产权资产管理有限公司 2021-01-19 CN disclosed
CN-107207691-B Viscosity modification of compositions containing organic phases 路博润先进材料公司 2020-11-10 CN disclosed
EP-3709956-A1 COSMETIC OR DERMATOLOGICAL COMPOSITIONS DSM IP Assets B.V. (NL) 2020-09-23 EP disclosed
US-20200170915-A1 METHOD FOR SOLUBILIZING POORLY WATER-SOLUBLE COSMETIC AGENTS ATHENION AG (CH) 2020-06-04 US disclosed
US-20050019278-A1 Sunscreen compositions as well as dihydropyridines and dihydropyranes ROCHE VITAMINS AG (CH) 2005-01-27 US disclosed
EP-1494642-A1 ORGANOSILICONE DERIVATIVES OF AMINO HYDROXYBENZOPHENONES AND THEIR USE AS UV-A FILTERS IN COSMETIC PREPARATIONS DSM IP Assets B.V. (NL) 2005-01-12 EP disclosed
EP-1474098-A1 SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES DSM IP Assets B.V. (NL) 2004-11-10 EP disclosed
WO-2004069216-A1 NOVEL STABILIZED CINNAMIC ESTER SUNSCREEN COMPOSITIONS DSM IP ASSETS B.V. (CH) 2004-08-19 WO disclosed
WO-2004007592-A1 SUNSCREENS DSM IP ASSETS B.V. (NL) 2004-01-22 WO disclosed
WO-2004000256-A1 BENZOXAZOLE AND BENZODIAZOLE UV-A SUNSCREENS DSM IP ASSETS B.V. (NL) 2003-12-31 WO disclosed
WO-2003086340-A1 ORGANOSILICONE DERIVATIVES OF AMINO HYDROXYBENZOPHENONES AND THEIR USE AS UV-A FILTERS IN COSMETIC PREPARATIONS DSM IP ASSETS B.V. (NL) 2003-10-23 WO disclosed
WO-2003068183-A1 SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES DSM IP ASSETS B.V. (NL) 2003-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050019278-A1 Sunscreen compositions as well as dihydropyridines and dihydropyranes DHPS, DSG1, DHODH NPC1 3091/4885RAB9A 1801/4885PKM 3489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.