Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892830 | 1.00 | ALDH1A1 (0.32) | ALDH1A1HSD17B10DPP7 | |
| SCHEMBL26198089 | 0.78 | KDM4E (0.32) | ALDH1A1HSD17B10 | |
| SCHEMBL28167992 | 0.75 | DPP7 (0.31) | DPP7 | |
| SCHEMBL11509027 | 0.74 | ALDH1A1 (0.35) | ALDH1A1HSD17B10DPP7 | |
| SCHEMBL27952447 | 0.72 | ALDH1A1 (0.30) | ALDH1A1HSD17B10 | |
| SCHEMBL7628030 | 0.72 | TRIM24 (0.32) | ALDH1A1 | |
| Methyl Alcohol SCHEMBL11610493 | 0.71 | TDP1 (0.38) | ALDH1A1HSD17B10 | |
| SCHEMBL2153044 | 0.67 | — | — | |
| SCHEMBL20942878 | 0.67 | CYP1A2 (0.31) | — | |
| SCHEMBL11562555 | 0.67 | ALDH1A1 (0.44) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10100198-B2 | Application of reduced dyes in imaging | LI-COR, INC. (US) | 2018-10-16 | — | — | US | disclosed |
| EP-2419478-B1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI COR INC (US) | 2018-02-28 | — | — | EP | disclosed |
| EP-2630196-B1 | CYANINE DYES AND THEIR CONJUGATES | LI COR INC (US) | 2017-09-06 | — | — | EP | disclosed |
| US-20170130050-A1 | APPLICATION OF REDUCED DYES IN IMAGING | LI-COR, INC. (US) | 2017-05-11 | — | — | US | disclosed |
| US-9470691-B2 | Application of reduced dyes in imaging | LI-COR, INC. (US) | 2016-10-18 | — | — | US | disclosed |
| US-9408924-B2 | Bioconjugates of cyanine dyes | LI-COR, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-9248203-B2 | Fluorescent imaging with substituted cyanine dyes | LI-COR, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-9089603-B2 | Fluorescent imaging with substituted cyanine dyes | LI-COR, INC. (US) | 2015-07-28 | — | — | US | disclosed |
| US-20150119553-A1 | BIOCONJUGATES OF CYANINE DYES | LI-COR, INC. | 2015-04-30 | — | — | US | disclosed |
| US-8927719-B2 | Cyanine dyes and their conjugates | LI-COR, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20130280172-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | MIDCAP FINANCIAL TRUST | 2013-10-24 | — | — | US | disclosed |
| US-20130274452-A1 | CYANINE DYES AND THEIR CONJUGATES | MIDCAP FINANCIAL TRUST | 2013-10-17 | — | — | US | disclosed |
| EP-2630196-A1 | CYANINE DYES AND THEIR CONJUGATES | LI-COR, INC. (US) | 2013-08-28 | — | — | EP | disclosed |
| US-8481752-B2 | Fluorescent imaging with substituted cyanine dyes | LI-COR, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| WO-2013044156-A1 | APPLICATION OF REDUCED DYES IN IMAGING | LI-COR, INC. (US) | 2013-03-28 | — | — | WO | disclosed |
| US-20130039860-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI-COR, INC. (US) | 2013-02-14 | — | — | US | disclosed |
| WO-2012054749-A1 | CYANINE DYES AND THEIR CONJUGATES | LI-COR, INC. (US) | 2012-04-26 | — | — | WO | disclosed |
| EP-2419478-A2 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI-COR, INC. (US) | 2012-02-22 | — | — | EP | disclosed |
| US-20100323389-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI-COR, INC. (US) | 2010-12-23 | — | — | US | disclosed |
| WO-2010121163-A2 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI-COR, INC. (US) | 2010-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274452-A1 | CYANINE DYES AND THEIR CONJUGATES | FCGR3B, QPCT, TIE1 | ALDH1A1 1529/4885HSD17B10 3531/4885DPP7 1972/4885 |
| US-10100198-B2 | Application of reduced dyes in imaging | HMOX2, HCCS, HMOX1 | ALDH1A1 624/4885HSD17B10 582/4885DPP7 3724/4885 |
| US-20130280172-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | TIE1, ALG1, MSR1 | ALDH1A1 1642/4885HSD17B10 3351/4885DPP7 2836/4885 |
| US-20100323389-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | MSR1, TIE1, ALG1 | ALDH1A1 1662/4885HSD17B10 3345/4885DPP7 2858/4885 |
| US-20150119553-A1 | BIOCONJUGATES OF CYANINE DYES | FCGR3B, FCGR2A, HCCS | ALDH1A1 2348/4885HSD17B10 3258/4885DPP7 2035/4885 |
| US-20130039860-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | TIE1, ALG1, MSR1 | ALDH1A1 1642/4885HSD17B10 3351/4885DPP7 2836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.