SCHEMBL6342145

SCHEMBL6342145

CCC(C)(C)c1c(-c2ccccc2)ccc(-c2ccccc2)c1C(C)(C)CC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.42
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
CASP3 P42574 1/20 0.42
RAB9A P51151 1/20 0.42
ATM Q13315 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
TAAR1 Q96RJ0 1/20 0.35
ESR2 Q92731 1/20 0.35
BACE1 P56817 1/20 0.34
ALOX5 P09917 1/20 0.34
DPP4 P27487 1/20 0.34
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34
ALDH1A1 P00352 4/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP2A6 P11509 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2550141 0.82 NPC1 (0.34) MAPK1NPC1LMNACASP3RAB9A
SCHEMBL6342144 0.80 PPARG (0.35) MAPK1NPC1LMNACASP3RAB9A
SCHEMBL10438748 0.80 NPC1 (0.38) MAPK1NPC1LMNACASP3RAB9A
SCHEMBL2544575 0.79 NPC1 (0.34) MAPK1NPC1LMNACASP3RAB9A
SCHEMBL127574 0.77 MAPK1 (0.41) MAPK1NPC1LMNACASP3RAB9A
SCHEMBL29128772 0.77 ALDH1A1 (0.40) MAPK1ESR2BACE1ALOX5DPP4
SCHEMBL677798 0.75 MAPK1 (0.40) MAPK1NPC1LMNACASP3RAB9A
SCHEMBL15457993 0.72 NPC1 (0.49) MAPK1NPC1LMNACASP3RAB9A
SCHEMBL700444 0.71 KIF11 (0.48) MAPK1NPC1LMNACASP3RAB9A
SCHEMBL10438750 0.71 PDCD1 (0.37) MAPK1NPC1LMNACASP3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662373-B2 Scintillating material composition to provide high light output NANOPTICS, INCORPORATED (US) 2020-05-26 US claimed
US-20170313935-A1 SCINTILLATING MATERIAL COMPOSITION TO PROVIDE HIGH LIGHT OUTPUT NANOPTICS, INCORPORATED 2017-11-02 US claimed
US-9657220-B2 Scintillating material composition to provide high light output NANOPTICS, INCORPORATED (US) 2017-05-23 US claimed
US-20150123036-A1 SCINTILLATING MATERIAL COMPOSITION TO PROVIDE HIGH LIGHT OUTPUT NANOPTICS, INCORPORATED 2015-05-07 US claimed
US-10662373-B2 Scintillating material composition to provide high light output NANOPTICS, INCORPORATED (US) 2020-05-26 US disclosed
US-20190072678-A1 MATERIALS, METHOD, AND APPARATUS FOR DETECTING NEUTRONS AND IONIZING RADIATION NANOPTICS, INCORPORATED 2019-03-07 US disclosed
EP-2689270-B1 MATERIALS, METHOD, AND APPARATUS FOR DETECTING NEUTRONS AND IONIZING RADIATION NANOPTICS INCORPORATED (US) 2018-12-05 EP disclosed
US-9897706-B2 Materials, method, and apparatus for detecting neutrons and ionizing radiation NANOPTICS, INCORPORATED (US) 2018-02-20 US disclosed
US-20170313935-A1 SCINTILLATING MATERIAL COMPOSITION TO PROVIDE HIGH LIGHT OUTPUT NANOPTICS, INCORPORATED 2017-11-02 US disclosed
US-9657220-B2 Scintillating material composition to provide high light output NANOPTICS, INCORPORATED (US) 2017-05-23 US disclosed
US-20150241573-A1 MATERIALS, METHOD, AND APPARATUS FOR DETECTING NEUTRONS AND IONIZING RADIATION NANOPTICS, INCORPORATED 2015-08-27 US disclosed
US-20150123036-A1 SCINTILLATING MATERIAL COMPOSITION TO PROVIDE HIGH LIGHT OUTPUT NANOPTICS, INCORPORATED 2015-05-07 US disclosed
US-8993968-B2 Materials, method, and apparatus for detecting neutrons and ionizing radiation NANOPTICS, INCORPORATED (US) 2015-03-31 US disclosed
EP-2689270-A2 MATERIALS, METHOD, AND APPARATUS FOR DETECTING NEUTRONS AND IONIZING RADIATION Nanoptics, Incorporated (US) 2014-01-29 EP disclosed
WO-2012135140-A2 MATERIALS, METHOD, AND APPARATUS FOR DETECTING NEUTRONS AND IONIZING RADIATION NANOPTICS, INCORPORATED (US) 2012-10-04 WO disclosed
US-20120241630-A1 MATERIALS, METHOD, AND APPARATUS FOR DETECTING NEUTRONS AND IONIZING RADIATION NANOPTICS, INCORPORATED (US) 2012-09-27 US disclosed
US-6977141-B2 Direct adsorption scintillation assay for measuring enzyme activity and assaying biochemical processes VICURON PHARMACEUTICALS INC. (US) 2005-12-20 US disclosed
US-20020015678-A1 DIRECT ADSORPTION SCINTILLATION ASSAY FOR MEASURING ENZYME ACTIVITY AND ASSAYING BIOCHEMICAL PROCESSES VICURON PHARMACEUTICALS INC. 2002-02-07 US disclosed
US-5466930-A Light source for calibrations of imaging devices FLORIDA STATE UNIVERSITY (US) 1995-11-14 US disclosed