Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CASP1 | P29466 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995310 | 0.89 | ADRA2B (0.51) | MAPTADRA2BHTTMEN1KMT2A | |
| SCHEMBL6267226 | 0.86 | MAPT (0.47) | MAPTADRA2BHTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6849297 | 0.85 | MAPT (0.46) | MAPTADRA2BHTTMEN1KMT2A | |
| SCHEMBL6340604 | 0.83 | EGFR (0.54) | MAPTADRA2BHTTMEN1KMT2A | |
| SCHEMBL7163158 | 0.80 | MAPT (0.61) | MAPTMEN1KMT2ACASP1KDM4E | |
| SCHEMBL6339193 | 0.77 | MAPT (0.44) | MAPTADRA2BMEN1KMT2ACASP1 | |
| SCHEMBL5164381 | 0.76 | POLB (0.53) | MAPTHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL2988180 | 0.76 | EGFR (0.54) | MAPTADRA2BHTTMEN1KMT2A | |
| SCHEMBL2473779 | 0.74 | ADRA2B (0.47) | MAPTADRA2BHTTMEN1KMT2A | |
| SCHEMBL11935858 | 0.74 | MAPT (0.67) | MAPTHTTMEN1KMT2ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936077-B2 | 1,3-diamino-4-(aminomethyl)—benzene derivatives and colorants containing the said compounds | WELLA AG (DE) | 2005-08-30 | — | — | US | disclosed |
| US-20030172471-A1 | 1,3-diamino-4-(aminomethyl) - benzene derivatives and colorants containing the said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030172471-A1 | 1,3-diamino-4-(aminomethyl) - benzene derivatives and colorants containing the said compounds | AOC1, DPYD, NDUFB4 | MAPT 898/4885ADRA2B 499/4885HTT 3827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.