Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | THRB | P10828 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | BLM | P54132 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.43 |
| ▸ | CASP1 | P29466 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2988180 | 0.90 | EGFR (0.54) | EGFRADRA2BALDH1A1L3MBTL1GAA | |
| SCHEMBL2995310 | 0.89 | ADRA2B (0.51) | EGFRADRA2BALDH1A1L3MBTL1GAA | |
| SCHEMBL6272046 | 0.86 | EGFR (0.54) | EGFRADRA2BALDH1A1L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL6269529 | 0.85 | EGFR (0.53) | EGFRADRA2BALDH1A1L3MBTL1GAA | |
| SCHEMBL6344706 | 0.83 | MAPT (0.47) | ADRA2BALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL7163125 | 0.83 | EGFR (0.74) | EGFRALDH1A1MAPTTDP1HSP90AA1 | |
| SCHEMBL6336237 | 0.82 | MAOB (0.47) | EGFRADRA2BALDH1A1MAPTMEN1 | |
| SCHEMBL2981070 | 0.79 | EGFR (0.59) | EGFRADRA2BALDH1A1MAPTTDP1 | |
| SCHEMBL7516084 | 0.79 | MAPT (0.55) | EGFRALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL2991048 | 0.79 | ADRA2B (0.53) | EGFRADRA2BALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936077-B2 | 1,3-diamino-4-(aminomethyl)—benzene derivatives and colorants containing the said compounds | WELLA AG (DE) | 2005-08-30 | — | — | US | disclosed |
| US-20030172471-A1 | 1,3-diamino-4-(aminomethyl) - benzene derivatives and colorants containing the said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030172471-A1 | 1,3-diamino-4-(aminomethyl) - benzene derivatives and colorants containing the said compounds | AOC1, DPYD, NDUFB4 | EGFR 4637/4885ADRA2B 499/4885ALDH1A1 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.