Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | PLK1 | P53350 | 5/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4244849 | 0.80 | RORC (0.43) | PTGDR2CYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL11796272 | 0.80 | CDC25A (0.43) | PTGDR2CDC25AMCL1PLK1ALDH1A1 | |
| SCHEMBL5456634 | 0.77 | CYP1A2 (0.67) | PTGDR2CYP1A2ALDH1A1LMNAKDM4E | |
| SCHEMBL8454150 | 0.76 | HTR7 (0.56) | CDC25APLK1ALDH1A1LMNAHTR7 | |
| SCHEMBL11883719 | 0.76 | MCL1 (0.46) | PTGDR2CDC25AMCL1PLK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3805296 | 0.76 | CYP1A2 (0.65) | PTGDR2CYP1A2ALDH1A1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL4242731 | 0.75 | ADRB2 (0.39) | PTGDR2CYP1A2ALDH1A1MEN1POLB | |
| SCHEMBL19100598 | 0.75 | PLK1 (0.45) | PTGDR2CDC25AMCL1PLK1ALDH1A1 | |
| SCHEMBL14268044 | 0.75 | NCF1 (0.45) | PTGDR2KDM4E | |
| SCHEMBL28605717 | 0.74 | PTGDR2 (0.57) | PTGDR2CDC25AMCL1PLK1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050165033-A1 | Use of indole-3-acetic acids in the treatment of asthma, copd and other diseases | ASTRAZENECA AB (SE) | 2005-07-28 | — | — | US | disclosed |
| EP-1474136-A1 | USE OF INDOLE-3-ACETIC ACIDS IN THE TREATMENT OF ASTHMA, COPD AND OTHER DISEASES | AstraZeneca AB (SE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066046-A1 | USE OF INDOLE-3-ACETIC ACIDS IN THE TREATMENT OF ASTHMA, COPD AND OTHER DISEASES | ASTRAZENECA AB (SE) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165033-A1 | Use of indole-3-acetic acids in the treatment of asthma, copd and other diseases | IDO1, IDO2, PTGDR2 | PTGDR2 3/4885CYP1A2 96/4885CDC25A 3362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.