Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349214 | 0.79 | KDM1A (0.44) | MEN1HPGDKMT2AL3MBTL1FFAR1 | |
| SCHEMBL7216153 | 0.74 | SMN1; SMN2 (0.32) | PPARD | |
| SCHEMBL30504353 | 0.74 | LMNA (0.47) | — | |
| SCHEMBL22042263 | 0.74 | LMNA (0.47) | — | |
| SCHEMBL6344981 | 0.73 | L3MBTL1 (0.38) | MEN1KMT2AL3MBTL1FFAR1PPARD | |
| SCHEMBL27293275 | 0.70 | THRA (0.49) | — | |
| SCHEMBL30620166 | 0.70 | THRA (0.49) | — | |
| SCHEMBL30448771 | 0.69 | EPHX2 (0.49) | MAPTSLC7A5 | |
| SCHEMBL7714353 | 0.69 | LMNA (0.34) | FFAR1 | |
| SCHEMBL31366917 | 0.68 | MAOB (0.40) | MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936602-B1 | Benzazepine derivatives, process for the preparation of the same and uses thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-30 | — | — | US | disclosed |
| EP-1186604-A1 | BENZAZEPINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-13 | — | — | EP | disclosed |