SCHEMBL6345196

SCHEMBL6345196

O=S(=O)(O)c1ccc(Nc2ccccc2)c2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 3/20 0.61
CHAT P28329 1/20 0.61
GAA P10253 3/20 0.58
ALDH1A1 P00352 3/20 0.58
KDM4E B2RXH2 2/20 0.58
MAPT P10636 2/20 0.58
RECQL P46063 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
POLB P06746 2/20 0.58
NSD2 O96028 2/20 0.58
CASP6 P55212 2/20 0.58
APEX1 P27695 1/20 0.58
APOBEC3A P31941 1/20 0.58
APOBEC3G Q9HC16 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TNNI3 P19429 1/20 0.57
TNNT2 P45379 1/20 0.57
TNNC1 P63316 1/20 0.57
HKDC1 Q2TB90 1/20 0.57
MEN1 O00255 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3755193 0.92 TTR (0.65) SNCACHATGAAALDH1A1KDM4E
SCHEMBL30924525 0.92 TTR (0.65) SNCACHATGAAALDH1A1KDM4E
SCHEMBL22501407 0.84 SNCA (0.63) SNCACHATGAAALDH1A1KDM4E
SCHEMBL27480237 0.83 SNCA (0.62) SNCACHATGAAALDH1A1KDM4E
SCHEMBL11652581 0.82 SNCA (0.64) SNCACHATGAAALDH1A1KDM4E
SCHEMBL4353216 0.81 MAPT (0.56) ALDH1A1KDM4EMAPTRECQLTDP1
SCHEMBL10892189 0.81 CTDSP1 (0.49) SNCACHATGAAALDH1A1KDM4E
SCHEMBL12878528 0.80 IDO1 (0.55) SNCACHATTNNI3TNNT2TNNC1
SCHEMBL4353264 0.80 ALDH1A1 (0.50) SNCACHATGAAALDH1A1TNNI3
SCHEMBL11962221 0.79 GAA (0.85) SNCACHATGAAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021062277-A1 FUNCTIONALIZED POLYMER FOR BATTERY APPLICATIONS CONAMIX INC. (US) 2021-04-01 WO disclosed
US-9370534-B2 Biocidal polymers WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2016-06-21 US disclosed
US-20150224135-A1 BIOCIDAL POLYMERS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-08-13 US disclosed
US-9034309-B2 Biocidal polymers WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-05-19 US disclosed
US-20050079150-A1 Copolymers conttaining styrene, unsaturated ester and acrylamide with polyethers WISCONSIN ALUMNI RESEARCH FOUNDATION 2005-04-14 US disclosed
WO-2005023931-A1 BIOCIDAL POLYMERS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2005-03-17 WO disclosed
US-20030070927-A1 Reagents and methods for fluorescent analysis of serum proteins MERCHANT MARK E (US) 2003-04-17 US disclosed
EP-0922227-A1 REAGENTS AND METHODS FOR FLUORESCENT ANALYSIS OF SERUM PROTEINS HELENA LABORATORIES CORPORATION (US) 1999-06-16 EP disclosed
WO-1998003875-A1 REAGENTS AND METHODS FOR FLUORESCENT ANALYSIS OF SERUM PROTEINS HELENA LABORATORIES CORPORATION (US) 1998-01-29 WO disclosed
US-4230456-A QUANTITATIVE ANALYSIS, COMPLEXING EASTMAN KODAK COMPANY (US) 1980-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150224135-A1 BIOCIDAL POLYMERS ACR, CFTR, ELANE SNCA 523/4885CHAT 509/4885GAA 113/4885
US-20050079150-A1 Copolymers conttaining styrene, unsaturated ester and acrylamide with polyethers TLR3, C9, LTC4S SNCA 1821/4885CHAT 2076/4885GAA 1237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.