Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.65 |
| ▸ | FABP4 | P15090 | 1/20 | 0.65 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.65 |
| ▸ | CDK2 | P24941 | 1/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.65 |
| ▸ | SNCA | P37840 | 2/20 | 0.64 |
| ▸ | CHAT | P28329 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.63 |
| ▸ | CDC25B | P30305 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30924525 | 1.00 | TTR (0.65) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL6345196 | 0.92 | SNCA (0.61) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL22501407 | 0.86 | SNCA (0.63) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL27480237 | 0.84 | SNCA (0.62) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL6264332 | 0.84 | FABP4 (0.70) | TTRFABP4CCNA2CDK2MAPK14 | |
| Ammonia Solution, Strong SCHEMBL1556275 | 0.82 | NR4A1 (0.71) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL29430564 | 0.80 | NR4A1 (0.68) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL18324651 | 0.80 | SNCA (0.71) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL6404861 | 0.80 | MEN1 (1.00) | FABP4GAAMEN1KMT2AKDM4E | |
| Sulfuric Acid SCHEMBL4742846 | 0.79 | CDC25B (0.79) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272156-B1 | USE OF ALCOHOL DEHYDROGENASE INHIBITORS FOR COSMETIC TREATMENT OF KERATINOUS MATERIALS | OREAL (FR) | 2006-05-31 | — | — | EP | claimed |
| US-20030138390-A1 | Use of alcohol dehydrogenase inhibitors for cosmetic treatment of keratinous materials | L'OREAL (FR) | 2003-07-24 | — | — | US | claimed |
| CN-111356764-B | Compositions and methods for reducing serum cholesterol and PCSK9 | 卡斯西部储备大学 | 2024-05-24 | — | — | CN | disclosed |
| US-11931339-B2 | Compositions and methods for treating tissue injury | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-03-19 | — | — | US | disclosed |
| US-20230190710-A1 | COMPOSITIONS AND METHODS OF REDUCING SERUM CHOLESTEROL AND PCSK9 | UNIV CASE WESTERN RESERVE (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230093056-A1 | COMPOSITIONS AND METHODS OF MODULATING S-NITROSYLATION | UNIV CASE WESTERN RESERVE (US) | 2023-03-23 | — | — | US | disclosed |
| US-20230054339-A1 | COMPOSITIONS AND METHODS OF MODULATING S-NITROSYLATION | UNIV CASE WESTERN RESERVE (US) | 2023-02-23 | — | — | US | disclosed |
| US-11576900-B2 | Compositions and methods of reducing serum cholesterol and PCSK9 | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-02-14 | — | — | US | disclosed |
| US-20230024914-A1 | METHODS OF TREATING RESPIRATORY DISORDERS | UNIV CASE WESTERN RESERVE (US) | 2023-01-26 | — | — | US | disclosed |
| US-11559498-B2 | Compositions and methods for in vivo lung and blood SNO repletion | UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER (US) | 2023-01-24 | — | — | US | disclosed |
| US-11389430-B2 | Methods of treating respiratory disorders | CASE WESTERN RESERVE UNIVERSITY (US) | 2022-07-19 | — | — | US | disclosed |
| CN-102549460-A | Coloring composition and color filter | TOYO INK SC HOLDINGS CO LTD | 2012-07-04 | — | — | CN | disclosed |
| US-20110195249-A1 | ADHESIVE COMPOSITION AND OPTICAL MEMBER | Wuxi Hengxin Optoelectronic Materials Co., Ltd. (CN) | 2011-08-11 | — | — | US | disclosed |
| US-20100305078-A1 | METALLO-OXIDOREDUCTASE INHIBITORS USING METAL BINDING MOIETIES IN COMBINATION WITH TARGETING MOIETIES | VIAMET PHARMACEUTICALS, INC. (US) | 2010-12-02 | — | — | US | disclosed |
| US-7786224-B2 | Liquid composition of alicyclic diepoxide, curing agent and/or curing accelerator | DAICEL CHEMICAL INDUSTRIES, LTD (JP) | 2010-08-31 | — | — | US | disclosed |
| US-20090281275-A1 | Curable resin compositions and interlayer dielectric films | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-2086546-A2 | METALLO-OXIDOREDUCTASE INHIBITORS USING METAL BINDING MOIETIES IN COMBINATION WITH TARGETING MOIETIES | Viamet Pharmaceuticals, Inc. (US) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008064311-A2 | METALLO-OXIDOREDUCTASE INHIBITORS USING METAL BINDING MOIETIES IN COMBINATION WITH TARGETING MOIETIES | VIAMET PHARMACEUTICALS, INC. (US) | 2008-05-29 | — | — | WO | disclosed |
| US-20050089930-A1 | Polypeptide fingerprinting methods | TARGET DISCOVERY, INC. (US) | 2005-04-28 | — | — | US | disclosed |
| US-20030138390-A1 | Use of alcohol dehydrogenase inhibitors for cosmetic treatment of keratinous materials | L'OREAL (FR) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230093056-A1 | COMPOSITIONS AND METHODS OF MODULATING S-NITROSYLATION | AKR1A1, AKR1B1, AKR1C2 | TTR 1233/4885FABP4 2160/4885CCNA2 4420/4885 |
| US-11576900-B2 | Compositions and methods of reducing serum cholesterol and PCSK9 | PCSK9, HMGCR, PCSK7 | TTR 502/4885FABP4 881/4885CCNA2 4677/4885 |
| US-20230054339-A1 | COMPOSITIONS AND METHODS OF MODULATING S-NITROSYLATION | AKR1B1, AKR1C2, AKR1A1 | TTR 1433/4885FABP4 1174/4885CCNA2 4233/4885 |
| US-20230024914-A1 | METHODS OF TREATING RESPIRATORY DISORDERS | GSR, GSS, TXNRD2 | TTR 2609/4885FABP4 2831/4885CCNA2 4479/4885 |
| US-11389430-B2 | Methods of treating respiratory disorders | GSR, GSS, TXNRD2 | TTR 2609/4885FABP4 2831/4885CCNA2 4479/4885 |
| US-20230190710-A1 | COMPOSITIONS AND METHODS OF REDUCING SERUM CHOLESTEROL AND PCSK9 | PCSK9, HMGCR, PCSK7 | TTR 502/4885FABP4 881/4885CCNA2 4677/4885 |
| US-11931339-B2 | Compositions and methods for treating tissue injury | PDK4, AK1, PDK1 | TTR 721/4885FABP4 120/4885CCNA2 3768/4885 |
| US-20100305078-A1 | METALLO-OXIDOREDUCTASE INHIBITORS USING METAL BINDING MOIETIES IN COMBINATION WITH TARGETING MOIETIES | NQO1, SOD1, MDH2 | TTR 1519/4885FABP4 3504/4885CCNA2 4272/4885 |
| US-11559498-B2 | Compositions and methods for in vivo lung and blood SNO repletion | GSR, GSS, HMOX1 | TTR 500/4885FABP4 1964/4885CCNA2 4093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.