Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 12/20 | 0.64 |
| ▸ | ADAMTS4 | O75173 | 7/20 | 0.64 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.64 |
| ▸ | MMP2 | P08253 | 14/20 | 0.60 |
| ▸ | MMP14 | P50281 | 6/20 | 0.60 |
| ▸ | MMP3 | P08254 | 5/20 | 0.59 |
| ▸ | MMP7 | P09237 | 5/20 | 0.59 |
| ▸ | MMP8 | P22894 | 5/20 | 0.59 |
| ▸ | MMP1 | P03956 | 4/20 | 0.58 |
| ▸ | MMP9 | P14780 | 2/20 | 0.58 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3615211 | 0.82 | MMP2 (0.79) | MMP13ADAMTS4ADAMTS5MMP2MMP14 | |
| SCHEMBL8288340 | 0.79 | MMP2 (0.62) | MMP13ADAMTS4ADAMTS5MMP2MMP14 | |
| SCHEMBL8285243 | 0.78 | ADAMTS4 (1.00) | MMP13ADAMTS4ADAMTS5MMP2MMP14 | |
| SCHEMBL1658611 | 0.78 | ADAMTS4 (1.00) | MMP13ADAMTS4ADAMTS5MMP2MMP14 | |
| SCHEMBL8091067 | 0.76 | MMP12 (0.73) | MMP13MMP2MMP14MMP3MMP9 | |
| SCHEMBL7761532 | 0.76 | MMP2 (1.00) | MMP13ADAMTS4MMP2MMP14MMP3 | |
| SCHEMBL7761520 | 0.76 | MMP2 (1.00) | MMP13ADAMTS4MMP2MMP14MMP3 | |
| SCHEMBL3617554 | 0.76 | MMP2 (0.69) | MMP13ADAMTS4ADAMTS5MMP2MMP14 | |
| SCHEMBL2380526 | 0.75 | MMP2 (1.00) | MMP13ADAMTS4MMP2MMP14MMP3 | |
| SCHEMBL3612416 | 0.75 | MMP2 (1.00) | MMP13ADAMTS4MMP2MMP14MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143422-A1 | Biaryl sulfonamides and methods for using same | WYETH (US) | 2005-06-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143422-A1 | Biaryl sulfonamides and methods for using same | STS, MMP3, AADAC | MMP13 13/4885ADAMTS4 113/4885ADAMTS5 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.