SCHEMBL6345970

SCHEMBL6345970

N=Nc1ccc(/N=N/c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
MAPT P10636 8/20 0.56
MEN1 O00255 7/20 0.56
KMT2A Q03164 7/20 0.56
RAB9A P51151 5/20 0.56
NPC1 O15118 5/20 0.56
PKM P14618 1/20 0.56
HTT P42858 1/20 0.56
TDP1 Q9NUW8 6/20 0.50
MAPK1 P28482 4/20 0.50
TSHR P16473 2/20 0.50
HSD17B10 Q99714 1/20 0.50
TRPA1 O75762 1/20 0.50
KDM4E B2RXH2 1/20 0.46
HSP90AA1 P07900 1/20 0.46
POLB P06746 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
L3MBTL1 Q9Y468 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2519093 1.00 ALDH1A1 (0.67) ALDH1A1MAPTMEN1KMT2ARAB9A
SCHEMBL54675 0.88
Hydrochloric Acid SCHEMBL28858836 0.85
Water SCHEMBL15153794 0.85 ALDH1A1 (0.50) ALDH1A1MAPTMEN1KMT2ARAB9A
SCHEMBL27539684 0.85
SCHEMBL2239365 0.85 ALDH1A1 (0.92) ALDH1A1MAPTMEN1KMT2ARAB9A
SCHEMBL90893 0.85 ALDH1A1 (0.92) ALDH1A1MAPTMEN1KMT2ARAB9A
SCHEMBL21024214 0.85 ALDH1A1 (0.92) ALDH1A1MAPTMEN1KMT2ARAB9A
SCHEMBL21023910 0.85 ALDH1A1 (0.92) ALDH1A1MAPTMEN1KMT2ARAB9A
SCHEMBL9418780 0.85 ALDH1A1 (0.92) ALDH1A1MAPTMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230181744-A1 COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES FUDAN UNIVERSITY (CN) 2023-06-15 US disclosed
CN-109369864-A A kind of preparation method of the block copolymer with photoresponse, reduction response and pH response 厦门大学 2019-02-22 CN disclosed
CN-104098555-B Method for synthesizing ultrashort-wavelength photochromic diarylethene compound by using imidazole-thiophene aromatic heterocycle and application of compound 江西科技师范大学 2017-03-22 CN disclosed
US-6841549-B1 Condensed imidazole compounds and a therapeutic agent for diabetes mellitus EISAI CO., LTD. (JP) 2005-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230181744-A1 COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES MAP1LC3B, MAP1LC3A, SQSTM1 ALDH1A1 897/4885MAPT 15/4885MEN1 3611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.