Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.59 |
| ▸ | MAX | P61244 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 4/20 | 0.56 |
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23447441 | 0.83 | MAPT (0.71) | MTORMAPTLMNAMEN1KMT2A | |
| SCHEMBL31609001 | 0.82 | MEN1 (0.61) | MYCMAXMAPTLMNAMEN1 | |
| SCHEMBL20804368 | 0.79 | NPC1 (0.65) | MAPTMEN1KMT2ARAB9AHPGD | |
| SCHEMBL2747411 | 0.78 | DDX3X (0.65) | MTORNAMPTMAPTMEN1KMT2A | |
| SCHEMBL28808075 | 0.78 | MTOR (0.76) | MTORNAMPTMAPTMEN1KMT2A | |
| SCHEMBL3461361 | 0.76 | CA2 (0.68) | NAMPTMAPTMEN1KMT2ARAB9A | |
| SCHEMBL12475154 | 0.76 | GPR35 (0.56) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL6339942 | 0.75 | ITGB3 (0.53) | MYCMAXMTORMAPTLMNA | |
| SCHEMBL20911013 | 0.75 | NPC1 (0.69) | NAMPTMAPTMEN1KMT2ARAB9A | |
| SCHEMBL3299625 | 0.74 | MYC (1.00) | MYCMAXMAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849639-B2 | Anticancer agents, antiinflamatory agents, osteoporosis, atherosclerosis | AMGEN INC. (US) | 2005-02-01 | — | — | US | disclosed |