Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 4/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.47 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.47 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357237 | 0.90 | AKR1C2 (0.64) | AKR1C2AKR1C1NR1H4AKR1C4AKR1C3 | |
| SCHEMBL6348340 | 0.87 | AKR1C2 (0.53) | AKR1C2AKR1C1SERPINE1KCNK2KCNK10 | |
| SCHEMBL6353739 | 0.81 | SERPINE1 (0.53) | AKR1C2AKR1C1SERPINE1KCNK2KCNK10 | |
| SCHEMBL6349831 | 0.78 | AKR1C2 (0.53) | AKR1C2AKR1C1KCNK2KCNK10MEN1 | |
| SCHEMBL1307965 | 0.78 | AKR1C2 (0.77) | AKR1C2AKR1C1KCNK2KCNK10AKR1C4 | |
| SCHEMBL567481 | 0.77 | PARP15 (0.51) | NR1H4MEN1KMT2A | |
| SCHEMBL6349385 | 0.77 | AKR1C2 (0.71) | AKR1C2AKR1C1SERPINE1KCNK2KCNK10 | |
| SCHEMBL6349607 | 0.76 | AKR1C2 (0.70) | AKR1C2AKR1C1SERPINE1NR1H4AKR1C4 | |
| SCHEMBL20512990 | 0.76 | SERPINE1 (0.66) | AKR1C2AKR1C1SERPINE1KCNK2KCNK10 | |
| SCHEMBL6346862 | 0.76 | AKR1C2 (0.80) | AKR1C2AKR1C1KCNK2KCNK10NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | AKR1C2 3012/4885AKR1C1 2615/4885SERPINE1 1929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.