Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.53 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233843 | 0.92 | SERPINE1 (0.60) | SERPINE1SMN1; SMN2LMNAMEN1PKM | |
| SCHEMBL6352349 | 0.90 | SERPINE1 (0.61) | SERPINE1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6351589 | 0.86 | KMT2A (0.75) | SERPINE1SMN1; SMN2LMNAMEN1PKM | |
| SCHEMBL11231268 | 0.84 | CHEK1 (0.70) | SERPINE1MEN1PKMKMT2ANPSR1 | |
| SCHEMBL6358123 | 0.84 | SERPINE1 (0.89) | SERPINE1MEN1KMT2AMAPTKCNK2 | |
| SCHEMBL11228267 | 0.82 | MEN1 (0.69) | SMN1; SMN2LMNAMEN1PKMKMT2A | |
| SCHEMBL11237527 | 0.82 | HPGD (0.67) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL420616 | 0.81 | SERPINE1 (1.00) | SERPINE1LMNAMAPTKCNK2KCNK10 | |
| SCHEMBL6352878 | 0.80 | SERPINE1 (0.76) | SERPINE1MEN1PKMKMT2ANPSR1 | |
| SCHEMBL6353639 | 0.79 | SERPINE1 (0.74) | SERPINE1TDP1KCNK2KCNK10AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | SERPINE1 1929/4885SMN1; SMN2 3015/4885LMNA 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.