Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | PKM | P14618 | 1/20 | 0.75 |
| ▸ | SERPINE1 | P05121 | 6/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.57 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6353180 | 0.92 | SERPINE1 (0.70) | KMT2ANPSR1MEN1PKMSERPINE1 | |
| SCHEMBL6358123 | 0.88 | SERPINE1 (0.89) | KMT2AMEN1SERPINE1MAPTHSD17B10 | |
| SCHEMBL6350271 | 0.86 | SERPINE1 (0.68) | KMT2ANPSR1MEN1PKMSERPINE1 | |
| SCHEMBL1308442 | 0.86 | KMT2A (1.00) | KMT2ANPSR1MEN1PKMSERPINE1 | |
| SCHEMBL420616 | 0.85 | SERPINE1 (1.00) | SERPINE1MAPTALDH1A1LMNAKCNK2 | |
| SCHEMBL6352878 | 0.83 | SERPINE1 (0.76) | KMT2ANPSR1MEN1PKMSERPINE1 | |
| SCHEMBL3785256 | 0.83 | F10 (0.77) | KMT2ANPSR1MEN1PKMMAPT | |
| SCHEMBL1307943 | 0.82 | SERPINE1 (0.70) | KMT2ANPSR1MEN1PKMSERPINE1 | |
| SCHEMBL6353639 | 0.82 | SERPINE1 (0.74) | SERPINE1HSD17B10ALDH1A1KCNK2KCNK10 | |
| SCHEMBL29838671 | 0.82 | SERPINE1 (1.00) | KMT2ANPSR1MEN1PKMSERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | KMT2A 3645/4885NPSR1 3975/4885MEN1 3274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.