Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1371732 | 0.98 | ALDH1A1 (0.64) | ALDH1A1KDM4ETDP1MDM2SMN1; SMN2 | |
| SCHEMBL4406529 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KDM4ETDP1MDM2SMN1; SMN2 | |
| SCHEMBL5538980 | 0.84 | KDM4E (0.61) | ALDH1A1KDM4ETDP1MDM2SMN1; SMN2 | |
| SCHEMBL2113038 | 0.83 | HTR1A (0.71) | ALDH1A1KDM4ETDP1MDM2SMN1; SMN2 | |
| SCHEMBL28080223 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4ETDP1MDM2SMN1; SMN2 | |
| SCHEMBL18088545 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1MDM2SMN1; SMN2 | |
| SCHEMBL21780812 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4ETDP1MDM2SMN1; SMN2 | |
| SCHEMBL5174282 | 0.80 | NPSR1 (0.71) | ALDH1A1KDM4ETSHRHTTNPSR1 | |
| SCHEMBL9533727 | 0.80 | HTR1A (0.64) | ALDH1A1KDM4ETDP1NPSR1HTR1A | |
| Hydrochloric Acid SCHEMBL9532906 | 0.79 | HTR1A (0.62) | ALDH1A1KDM4ETDP1NPSR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307525-A | Iridoid compound, preparation method thereof, pharmaceutical composition and application thereof | 安徽中医药大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118307525-A | Iridoid compound, preparation method thereof, pharmaceutical composition and application thereof | 安徽中医药大学 | 2024-07-09 | — | — | CN | disclosed |
| US-20230374034-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2023-11-23 | — | — | US | disclosed |
| US-20230374034-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2023-11-23 | — | — | US | disclosed |
| WO-2022075486-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2022-04-14 | — | — | WO | disclosed |
| WO-1999048911-A1 | MONOBACTAM ENZYME INHIBITORS | NAEJA PHARMACEUTICAL INC. (GB) | 1999-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230374034-A1 | NOVEL BICYCLIC COMPOUNDS | NOTCH1, NOTCH2, HES1 | ALDH1A1 1622/4885KDM4E 1654/4885TDP1 4179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.