Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.55 |
| ▸ | PPARD | Q03181 | 9/20 | 0.55 |
| ▸ | PPARA | Q07869 | 8/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.48 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.48 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352169 | 0.93 | PPARG (0.55) | PPARGPPARDPPARAFABP4AKR1C2 | |
| SCHEMBL6349494 | 0.89 | PPARG (0.65) | PPARGPPARDPPARAHDAC1FABP4 | |
| SCHEMBL6359265 | 0.87 | MEN1 (0.57) | PPARGPPARDPPARAHDAC1FABP4 | |
| SCHEMBL6350313 | 0.86 | HDAC1 (0.68) | PPARGPPARDPPARAHDAC1FABP4 | |
| SCHEMBL6357902 | 0.86 | PPARG (0.49) | PPARGPPARDPPARAHDAC1FABP4 | |
| SCHEMBL6351914 | 0.83 | PPARG (0.65) | PPARGPPARDPPARA | |
| SCHEMBL6360128 | 0.79 | CYP2C19 (0.52) | PPARGPPARDPPARAHDAC1HDAC6 | |
| SCHEMBL6350593 | 0.78 | PPARG (0.69) | PPARGPPARDPPARAAKR1C2AKR1C1 | |
| SCHEMBL6360570 | 0.78 | KCNK2 (0.68) | HDAC1AKR1C2AKR1C1KCNK2KCNK10 | |
| SCHEMBL6350776 | 0.78 | AKR1C2 (0.56) | PPARGPPARDPPARAAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | disclosed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | PPARG 3572/4885PPARD 2519/4885PPARA 2335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.