Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.68 |
| ▸ | PPARG | P37231 | 11/20 | 0.68 |
| ▸ | PPARD | Q03181 | 11/20 | 0.68 |
| ▸ | PPARA | Q07869 | 10/20 | 0.68 |
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6350433 | 0.86 | PPARG (0.55) | HDAC1HDAC6PPARGPPARDPPARA | |
| SCHEMBL6349494 | 0.86 | PPARG (0.65) | HDAC1HDAC6PPARGPPARDPPARA | |
| SCHEMBL6359265 | 0.85 | MEN1 (0.57) | HDAC1HDAC6PPARGPPARDPPARA | |
| SCHEMBL31159337 | 0.81 | HDAC1 (1.00) | HDAC1HDAC6PPARGPPARDPPARA | |
| SCHEMBL6351914 | 0.81 | PPARG (0.65) | PPARGPPARDPPARA | |
| SCHEMBL6352169 | 0.81 | PPARG (0.55) | PPARGPPARDPPARAMAPTFABP4 | |
| SCHEMBL6357902 | 0.80 | PPARG (0.49) | HDAC1PPARGPPARDPPARAMAPT | |
| SCHEMBL31159375 | 0.80 | HDAC1 (0.77) | HDAC1HDAC6PPARGPPARDPPARA | |
| SCHEMBL6349859 | 0.79 | MAPT (0.76) | MAPT | |
| SCHEMBL31159555 | 0.79 | HTR6 (0.76) | HDAC1HDAC6PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | disclosed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | HDAC1 3341/4885HDAC6 1485/4885PPARG 3572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.