SCHEMBL635055

SCHEMBL635055

Cc1noc(C)c1N=C=O

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
POLB P06746 1/20 0.35
MAPK1 P28482 1/20 0.35
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
BRD4 O60885 3/20 0.31
BRD2 P25440 1/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2825797 0.78 MAPT (0.39) MAPTL3MBTL1POLBMAPK1GABRA1
SCHEMBL2407274 0.72 BRD4 (0.43) MAPTGABRA1GABRB2BRD4BRD2
SCHEMBL238904 0.71 PTGS2 (0.53) MAPTPOLBBRD4BRD2CYP3A4
SCHEMBL15920150 0.70
SCHEMBL1904432 0.70 BRD4 (0.38) MAPTL3MBTL1POLBMAPK1BRD4
SCHEMBL856532 0.70 CYP3A4 (0.34) CYP3A4
SCHEMBL14405559 0.67
SCHEMBL96415 0.65
SCHEMBL27500197 0.65 MAPT (0.37) MAPTL3MBTL1POLBMAPK1BRD4
SCHEMBL57779 0.65 CYP3A4 (0.46) GABRA1GABRB2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713378-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2026-03-25 EP disclosed
EP-3774961-B1 ADDUCTS OF AMINE CATALYSTS FOR PRODUCING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2025-01-15 EP disclosed
WO-2024260055-A1 MODIFIED REGENERANT FOR POLYESTER ELASTOMER AND USE THEREOF 苏州申赛新材料有限公司 2024-12-26 WO disclosed
WO-2024236000-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2024-11-21 WO disclosed
EP-4464727-A1 ESTERIFIED ETHANOLAMINES FOR THE PREPARATION OF ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2024-11-20 EP disclosed
CN-114380874-B Macrolide antibiotics, preparation method and application thereof 中国医学科学院医药生物技术研究所 2024-06-21 CN disclosed
US-20240150515-A1 Low Viscosity Catalyst Compositions for Producing Isocyanurate Polymers COVESTRO DEUTSCHLAND AG (DE) 2024-05-09 US disclosed
EP-4298140-A1 LOW VISCOSITY CATALYST COMPOSITIONS FOR PRODUCING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2024-01-03 EP disclosed
EP-3280707-B1 BICYCLIC QUINAZOLINONE DERIVATIVES HOFFMANN LA ROCHE (CH) 2023-12-20 EP disclosed
CN-116478447-B Modified regenerant of polyester elastomer and application thereof 苏州申赛新材料有限公司 2023-08-29 CN disclosed
US-6608077-B2 Sulfonamide substituted diphenyl urea derivatives; treating chemokine mediated disease SMITHKLINE BEECHAM CORPORATION 2003-08-19 US disclosed
US-6559162-B2 Electrophysiological activity ASTRAZENECA AB (SE) 2003-05-06 US disclosed
US-20030055286-A1 Sulfonamide substituted diphenyl urea derivatives; treating chemokine mediated disease SMITHKLINE BEECHAM CORPORATION 2003-03-20 US disclosed
EP-1261336-A2 IL-8 RECEPTOR ANTAGONISTS SmithKline Beecham Corporation (US) 2002-12-04 EP disclosed
US-20020137766-A1 Azabicyclooctane derivatives useful in the treatment of cardiac arrhythmias ASTRAZENECA AB (SE) 2002-09-26 US disclosed
WO-2001068568-A2 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 2001-09-20 WO disclosed
EP-0695748-B1 Tetrazolinone herbicides BAYER AGROCHEM KK (JP) 1999-05-06 EP disclosed
US-5589439-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1996-12-31 US disclosed
EP-0695748-A1 Tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1996-02-07 EP disclosed
US-4863947-A PESTICIDES, INSECTICIDES ROHM AND HAAS (US) 1989-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055286-A1 Sulfonamide substituted diphenyl urea derivatives; treating chemokine mediated disease CXCL8, CCR8, CCL2 MAPT 2058/4885L3MBTL1 3645/4885POLB 3046/4885
US-20020137766-A1 Azabicyclooctane derivatives useful in the treatment of cardiac arrhythmias KCNH1, KCNH2, KCNH3 MAPT 4857/4885L3MBTL1 2420/4885POLB 916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.