Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516859 | 0.93 | KMT2A (0.46) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6516854 | 0.93 | KMT2A (0.46) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6352550 | 0.87 | HRH2 (0.39) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7541560 | 0.87 | ALDH1A1 (0.36) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6344211 | 0.87 | LMNA (0.40) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7547077 | 0.86 | ALDH1A1 (0.40) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6516899 | 0.85 | LMNA (0.45) | LMNAMEN1KMT2APMP22NPSR1 | |
| SCHEMBL6343215 | 0.84 | GABRA1 (0.38) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5240544 | 0.83 | MYC (0.39) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5204621 | 0.82 | MYC (0.38) | LMNAALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936602-B1 | Benzazepine derivatives, process for the preparation of the same and uses thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-30 | — | — | US | disclosed |
| EP-1186604-A1 | BENZAZEPINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-13 | — | — | EP | disclosed |