Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.48 |
| ▸ | TUBB | P07437 | 7/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6341857 | 0.80 | TUBB1 (0.60) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4967750 | 0.78 | CYP19A1 (0.70) | GAATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL8530355 | 0.78 | CA2 (0.48) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6343591 | 0.76 | ALDH1A1 (0.59) | GAATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL17057776 | 0.76 | GAA (0.65) | GAATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL17057716 | 0.76 | GAA (0.65) | GAATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6343808 | 0.75 | GAA (0.54) | GAATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL31090146 | 0.73 | GAA (0.77) | GAATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6865547 | 0.73 | GAA (1.00) | GAATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL357294 | 0.71 | GAA (0.74) | GAACYP19A1ALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050187246-A1 | Cell proliferation inhibitors | LI QUN (US) | 2005-08-25 | — | — | US | claimed |
| US-20030096856-A1 | Cell proliferation inhibitors | ABBVIE INC. | 2003-05-22 | — | — | US | claimed |
| EP-1181269-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | claimed |
| WO-2000073264-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2000-12-07 | — | — | WO | claimed |
| US-20050187246-A1 | Cell proliferation inhibitors | LI QUN (US) | 2005-08-25 | — | — | US | disclosed |
| US-6924304-B2 | Cell proliferation inhibitors | ABBOTT LABORATORIES (US) | 2005-08-02 | — | — | US | disclosed |
| US-20030096856-A1 | Cell proliferation inhibitors | ABBVIE INC. | 2003-05-22 | — | — | US | disclosed |
| US-6521658-B1 | Cell proliferation inhibitors | ABBOTT LABORATORIES | 2003-02-18 | — | — | US | disclosed |
| EP-1181269-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000073264-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2000-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096856-A1 | Cell proliferation inhibitors | MKI67, CCNI, CCNA1 | GAA 679/4885TUBB1 102/4885TUBB4A 299/4885 |
| US-20050187246-A1 | Cell proliferation inhibitors | MKI67, CCNI, CCNC | GAA 522/4885TUBB1 123/4885TUBB4A 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.