Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.45 |
| ▸ | TUBB | P07437 | 5/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6338880 | 0.85 | TUBB4A (0.60) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8529307 | 0.83 | PTGS2 (0.50) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6341857 | 0.78 | TUBB1 (0.60) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8793443 | 0.78 | CA2 (0.52) | CA2SMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL6351464 | 0.78 | GAA (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10614759 | 0.75 | PTGS2 (0.61) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29689431 | 0.74 | TUBB4A (0.74) | CA2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20696534 | 0.74 | TUBB4A (0.74) | CA2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20821454 | 0.74 | PTGS2 (0.59) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2759472 | 0.74 | AR (0.49) | CA2SMN1; SMN2ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840991-A | 3,4,5-TRIHYDROXYBENZYL-4-HYDROXYPHENYL THIOETHER | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 1998-11-24 | — | — | US | claimed |
| US-5840991-A | 3,4,5-TRIHYDROXYBENZYL-4-HYDROXYPHENYL THIOETHER | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 1998-11-24 | — | — | US | disclosed |