SCHEMBL357294

SCHEMBL357294

CCc1ccc(OC)c(N)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.74
ALDH1A1 P00352 5/20 0.55
CYP3A4 P08684 1/20 0.55
MEN1 O00255 1/20 0.53
MAPT P10636 1/20 0.53
THRB P10828 1/20 0.53
KMT2A Q03164 1/20 0.53
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CYP19A1 P11511 1/20 0.47
CA2 P00918 1/20 0.47
PTGS2 P35354 1/20 0.47
PDE4A P27815 2/20 0.46
PDE4B Q07343 2/20 0.46
PDE4C Q08493 2/20 0.46
PDE4D Q08499 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
APP P05067 1/20 0.46
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29712870 1.00 GAA (0.74) GAAALDH1A1CYP3A4MEN1MAPT
SCHEMBL31090146 0.85 GAA (0.77) GAAALDH1A1CYP3A4MEN1MAPT
SCHEMBL6865547 0.85 GAA (1.00) GAAALDH1A1CYP3A4MEN1MAPT
SCHEMBL13181092 0.84 GAA (0.69) GAAALDH1A1CYP3A4MEN1MAPT
SCHEMBL1725006 0.83 GAA (0.74) GAAALDH1A1CYP3A4MEN1MAPT
SCHEMBL5831938 0.83 ALDH1A1 (0.74) GAAALDH1A1CYP3A4HTTCYP19A1
SCHEMBL15604545 0.82 GAA (0.71) GAAALDH1A1CYP3A4MEN1MAPT
SCHEMBL12510496 0.82 GAA (0.71) GAAALDH1A1CYP3A4MEN1MAPT
SCHEMBL11133251 0.82 HSD17B10 (0.56) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL2888639 0.82 GAA (0.71) GAAALDH1A1CYP3A4MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024260368-A1 BENZOFURAN DERIVATIVE AND PREPARATION METHOD FOR BENZOFURAN DERIVATIVE INTERMEDIATE 江苏恒瑞医药股份有限公司 2024-12-26 WO claimed
US-9249091-B2 Post-treated sulfurized salt of an alkyl-substituted hydroxyaromatic composition CHEVRON ORONITE COMPANY LLC (US) 2016-02-02 US claimed
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE COMPANY LLC (US) 2013-06-27 US claimed
US-7056986-B2 ethylene monomer can be a vinyl ketone, ether, ester, halide, nitrile, aromatic, or an allyl ether; acrylic monomer can be a mono- or diacid or monoester of a diacid; a monoamine, a guanidine compound, and an aromatic diamine; improved vulcanizability, balance between processability and compression set DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-06-06 US claimed
US-12479834-B2 Phenol compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2025-11-25 US disclosed
WO-2024260368-A1 BENZOFURAN DERIVATIVE AND PREPARATION METHOD FOR BENZOFURAN DERIVATIVE INTERMEDIATE 江苏恒瑞医药股份有限公司 2024-12-26 WO disclosed
CN-118546107-A 2-Thiazole aminophenol derivatives and application thereof 中国药科大学 2024-08-27 CN disclosed
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO. LTD. (JP) 2023-02-16 US disclosed
EP-4067343-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF Taiho Pharmaceutical Co., Ltd. (JP) 2022-10-05 EP disclosed
CN-110249004-B Polyimide precursor composition 东京应化工业株式会社 2022-07-19 CN disclosed
CN-108774561-B Sulfurized salts of post-treated alkyl-substituted hydroxyaromatic compositions 雪佛龙奥伦耐有限责任公司 2022-07-01 CN disclosed
CN-108389512-B Laminate, flexible device, and method for producing laminate 东京应化工业株式会社 2022-04-15 CN disclosed
US-5244860-A PRESSURE-SENSITIVE RECORDING AND TRANSFER MATERIAL CIBA-GEIGY CORPORATION (US) 1993-09-14 US disclosed
US-5162550-A BISPHTHALIDE LACTONES, THEIR PREPARATION AND THE USE THEREOF IN RECORDING MATERIALS CIBA-GEIGY CORPORATION (US) 1992-11-10 US disclosed
EP-0465403-A1 Pressure sensitive recording and transfer material CIBA-GEIGY AG (CH) 1992-01-08 EP disclosed
EP-0465402-A1 Heat sensitive recording material CIBA-GEIGY AG (CH) 1992-01-08 EP disclosed
EP-0415885-A1 Bis-Phthalideactones, process for their preparation, and their use in recording materials CIBA-GEIGY AG (CH) 1991-03-06 EP disclosed
EP-0400647-A1 Polyazo dye compounds having vinylsulfone type and pyridinium type fiber reactive groups SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-12-05 EP disclosed
US-4378313-A FOR CELLULOSE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-03-29 US disclosed
EP-0021105-B1 REACTIVE DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR DYEING CELLULOSE FIBERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION TST, PAH, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 GAA 1861/4885ALDH1A1 814/4885CYP3A4 2118/4885
US-12479834-B2 Phenol compound or salt thereof REN, MLX, MYB GAA 2659/4885ALDH1A1 287/4885CYP3A4 2867/4885
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF MYB, MLX, EP300 GAA 3048/4885ALDH1A1 235/4885CYP3A4 3428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.