Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | SPR | P35270 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.43 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10274489 | 0.81 | KCNH2 (0.52) | DRD4MAP4K4HSD11B1SPRUSP30 | |
| SCHEMBL18239070 | 0.81 | DRD4 (0.47) | DRD4MAP4K4HSD11B1SPRUSP30 | |
| SCHEMBL6347014 | 0.80 | HSD11B1 (0.53) | DRD4MAP4K4HSD11B1SPRUSP30 | |
| SCHEMBL6358179 | 0.80 | DRD4 (0.48) | DRD4HSD11B1SPRUSP30KDM4E | |
| Hydrochloric Acid SCHEMBL4002709 | 0.78 | DRD4 (0.47) | DRD4HSD11B1SPRUSP30KDM4E | |
| SCHEMBL19016266 | 0.77 | DRD4 (0.45) | DRD4MAP4K4HSD11B1SPRUSP30 | |
| SCHEMBL31754520 | 0.77 | USP30 (0.59) | DRD4MAP4K4HSD11B1USP30 | |
| SCHEMBL17886898 | 0.77 | DRD4 (0.45) | DRD4MAP4K4HSD11B1SPRUSP30 | |
| SCHEMBL17896380 | 0.77 | DRD2 (0.47) | DRD4MAP4K4HSD11B1SPRKDM5A | |
| SCHEMBL1515110 | 0.77 | ALDH1A1 (0.46) | DRD4MAP4K4HSD11B1SPRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | CYP19A1, SHBG, CYP17A1 | DRD4 1272/4885MAP4K4 2508/4885HSD11B1 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.