Tepirindole

Tepirindole

SCHEMBL635174

CCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 10/20 0.72
OPRM1 P35372 1/20 0.71
OPRK1 P41145 1/20 0.71
DRD2 P14416 10/20 0.68
HTR6 P50406 10/20 0.68
HTR1A P08908 9/20 0.68
HTR7 P34969 9/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tepirindole SCHEMBL29710897 1.00 SLC6A4 (0.72) SLC6A4OPRM1OPRK1DRD2HTR6
Tepirindole SCHEMBL11307437 1.00 SLC6A4 (0.72) SLC6A4OPRM1OPRK1DRD2HTR6
SCHEMBL11327571 0.91 OPRM1 (0.73) SLC6A4OPRM1OPRK1DRD2HTR6
Hydrochloric Acid SCHEMBL11320856 0.91 OPRM1 (0.73) SLC6A4OPRM1OPRK1DRD2HTR6
SCHEMBL10366941 0.88 OPRM1 (0.71) SLC6A4OPRM1OPRK1DRD2HTR6
SCHEMBL15064205 0.88 OPRM1 (0.71) SLC6A4OPRM1OPRK1DRD2HTR6
SCHEMBL791317 0.86 DRD2 (0.69) SLC6A4OPRM1OPRK1DRD2HTR6
SCHEMBL11224825 0.86 DRD2 (0.69) SLC6A4OPRM1OPRK1DRD2HTR6
Hydrochloric Acid SCHEMBL11233239 0.86 KDM4E (0.57) SLC6A4OPRM1OPRK1DRD2HTR1A
SCHEMBL793144 0.85 DRD2 (0.71) SLC6A4OPRM1OPRK1DRD2HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1931320-B1 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL DOSAGE FORM COMPRISING THE SAME FLAMEL IRELAND LTD (IE) 2022-06-15 EP claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
US-20090220611-A1 Microparticles With Modified Release of At Least One Active Principle and Oral Pharmaceutical Form Comprising Same FLAMEL TECHNOLOGIES, S.A. (FR) 2009-09-03 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
EP-1931320-A2 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL GALENIC FORM COMPRISING SAME Flamel Technologies (FR) 2008-06-18 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
WO-2007036671-A2 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL GALENIC FORM COMPRISING SAME FLAMEL TECHNOLOGIES (FR) 2007-04-05 WO claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 EP disclosed
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2026-02-05 US disclosed
US-12465564-B2 Oral and nasal compositions and methods of treatment AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
US-5795909-A ANTICARCINOGENIC AND ANTITUMOR AGENTS; BREAST, COLON, OVARIANCANCERS NEUROMEDICA, INC. (US) 1998-08-18 US disclosed
EP-0003199-B1 TETRAHYDROPYRIDINYL INDOLE DERIVATIVES AND THEIR SALTS, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1981-11-11 EP disclosed
EP-0003199-A2 Tetrahydropyridinyl indole derivatives and their salts, process for their preparation, their use as medicines and pharmaceutical compositions containing them ROUSSEL-UCLAF (FR) 1979-07-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES SORD, SLC6A13, CACNA1A SLC6A4 120/4885OPRM1 1993/4885OPRK1 2725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.