Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 8/20 | 0.58 |
| ▸ | DRD2 | P14416 | 6/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | HTR7 | P34969 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6351426 | 0.88 | HTR1A (0.81) | HTR1AADORA1DRD4DRD2HTR2A | |
| SCHEMBL6353873 | 0.87 | DRD4 (0.74) | HTR1AMEN1KMT2APOLBDRD4 | |
| SCHEMBL6346697 | 0.86 | ADORA1 (0.56) | HTR1AMEN1KMT2APOLBADORA1 | |
| SCHEMBL6357381 | 0.86 | MEN1 (0.60) | HTR1AMEN1KMT2APOLBDRD4 | |
| SCHEMBL9080030 | 0.84 | HTR1A (0.61) | HTR1AMEN1KMT2APOLBDRD4 | |
| SCHEMBL6359334 | 0.84 | KMT2A (0.67) | HTR1AMEN1KMT2APOLBDRD4 | |
| SCHEMBL6350293 | 0.82 | MEN1 (0.68) | HTR1AMEN1KMT2APOLBDRD4 | |
| SCHEMBL4006366 | 0.81 | THRB (0.82) | MEN1KMT2APOLBDRD4DRD2 | |
| SCHEMBL6360622 | 0.81 | DRD4 (0.67) | HTR1APOLBADORA1DRD4DRD2 | |
| SCHEMBL4874296 | 0.80 | ALDH1A1 (0.71) | HTR1AMEN1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | CYP19A1, SHBG, CYP17A1 | HTR1A 871/4885MEN1 3181/4885KMT2A 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.