Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352804 | 0.85 | AKR1C2 (0.58) | PKMAKR1C2AKR1C1NPC1MAPT | |
| SCHEMBL6359832 | 0.83 | MAPT (0.57) | PKMAKR1C2AKR1C1NPC1RAB9A | |
| SCHEMBL6359133 | 0.81 | AKR1C2 (0.68) | PKMAKR1C2AKR1C1MAPTSMN1; SMN2 | |
| SCHEMBL6353682 | 0.79 | AKR1C2 (0.71) | AKR1C2AKR1C1MAPTCYP3A4MEN1 | |
| SCHEMBL30580504 | 0.79 | AKR1C3 (0.63) | AKR1C2AKR1C1NPC1RAB9AMAPT | |
| SCHEMBL269614 | 0.79 | AKR1C3 (0.63) | AKR1C2AKR1C1NPC1RAB9AMAPT | |
| SCHEMBL6349859 | 0.78 | MAPT (0.76) | PKMAKR1C2AKR1C1MAPTSMN1; SMN2 | |
| SCHEMBL22720157 | 0.78 | AKR1C3 (0.62) | AKR1C2MAPTSMN1; SMN2AKR1C3MEN1 | |
| SCHEMBL6359602 | 0.78 | AKR1C2 (0.55) | PKMAKR1C2AKR1C1NPC1RAB9A | |
| SCHEMBL7797762 | 0.77 | KDM4E (0.79) | PKMMAPTSMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | PKM 4573/4885AKR1C2 3012/4885AKR1C1 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.